Autoimmune and Autoinflammatory Genetics Study
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1+
SponsorNYU Langone Health
About this trial
This is an exploratory natural history protocol that will enroll patients with known genetic diseases, such as VEXAS syndrome, or as yet undiagnosed disorders of inflammation with the goal of improving our understanding of disease processes. Blood, saliva, hair, nail, or buccal samples may be collected for genetic analysis, blood samples will be obtained for immunologic and other functional studies, and a small number of subjects may undergo skin biopsy.
Eligibility criteria
Qualifiers
Stated willingness to participate in study procedures (which at the very least includes providing a mail-in blood or saliva sample for genetic analysis);
Regardless of sex assigned at birth, at least one month of age;
A medical history that, in the expert opinion of the PI and study team, is consistent with the possibility of autoinflammatory disease or known diagnosis of an autoinflammatory disease, such as VEXAS syndrome; and
Ability of the subject, parents (in the case of children), or Legally Authorized Representative to understand and the willingness to sign a written informed consent document.
Disqualifiers
None
Trial design
Treatments tested in this trial
- Not listed
Trial groups
1,500 Participants
are grouped into 3 trial groupsLocations
2NYC H+H/Bellevue10016, New YorkNew York, United States
NYU Langone Health10016, New YorkNew York, United States
Sponsors and collaborators
NYU Langone Health
Lead sponsor
Source ClinicalTrials.gov