[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100439135":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":30,"responsibleParty":51,"collaborators":19,"id":54,"slug":19,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":19,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":19,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":33,"whyStopped":19,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"University of Washington","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Transplantation","EXPERIMENTAL","Endovascular infusion",[13],"Other: Endovascular autologous mitochondrial transplantation",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Endovascular autologous mitochondrial transplantation","During standard-of-care endovascular reperfusion procedure, subjects will have autologous mitochondria infused via microcatheter into ischemic brain.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Melanie S Walker, MD","PRINCIPAL_INVESTIGATOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Study Coordinator","CONTACT","206-897-5802","sanslab@uw.edu",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Harborview Medical Center","RECRUITING","Seattle","Washington","98104","United States",{"type":39,"coordinates":40},"Point",[41,42],-122.33207,47.60621,{"lat":42,"lon":41},[45,48],{"name":46,"role":27,"phone":47,"phoneExt":19,"email":19},"Melanie Walker, MD","206-744-3000",{"name":49,"role":50,"phone":19,"phoneExt":19,"email":19},"Michael Levitt, MD","SUB_INVESTIGATOR",{"type":23,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Melanie Walker","Professor, School of Medicine","100439135",false,"NCT04998357","Autologous Mitochondrial Transplant for Cerebral Ischemia","Study Title: Autologous Mitochondrial Transplant for Cerebral Ischemia","Inclusion Criteria:\n\n* Eligible for endovascular thrombectomy to treat acute large vessel occlusion\n* Eligible for angioplasty (microcatheter-based balloon\u002Fmechanical and chemical angioplasty) to treat acute cerebral vasospasm after aneurysmal subarachnoid hemorrhage\n* Subjects for whom there is likely to be enough time to obtain meaningful consent from patient or legally-authorized representative\n\nExclusion Criteria:\n\n* Unable to receive a brain MRI scan\n* Known mitochondrial disease\n* Hemodynamically unstable patients in whom standard of care endovascular reperfusion treatment cannot safely be performed or completed","ALL","18 Years","85 Years",{"count":64,"type":65},20,"ESTIMATED","INTERVENTIONAL",[68],"NA","The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.",[71],"Cerebral Ischemia",[73,74],"autologous mitochondrial transplantation","ischemic stroke","2025-05-15",{"date":77,"type":78},"2025-05-21","ACTUAL",{"date":80,"type":78},"2021-04-29",{"date":82,"type":65},"2026-10-29",{"name":5,"class":6},1]