[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562426":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":55,"collaborators":58,"id":62,"slug":25,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":25,"enrollmentInfo":70,"targetDuration":25,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":92,"whyStopped":25,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University of Illinois at Chicago","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"GET Up PD","EXPERIMENTAL","Remotely-coached\u002Fguided, home-based program delivered using telerehabilitation focusing on aerobic fitness and muscle strength as a mode of training",[13],"Behavioral: GET Up PD",{"label":15,"type":16,"description":17,"interventionNames":18},"Stretching and Flexibility","ACTIVE_COMPARATOR","Remotely-coached\u002Fguided, home-based program delivered using telerehabilitation focusing on stretching and range of motion as the mode of training",[19],"Behavioral: Stretching and Flexibility",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","* The exercise training prescription involves performing 3 days per week and include (a) aerobic exercise: 30+ minutes of moderate-intensity walking (≥100 steps\u002Fmin) monitored by a waist-worn pedometer, and (b) resistance training: 1-3 sets, 8-12 repetitions of 5-10 exercises targeting lower and upper body, and core muscle groups using elastic bands.\n* Other components of the GET Up PD program include appropriate exercise equipment (pedometer, resistance bands), one-on-one coaching sessions via Zoom, action-planning via calendars, logbooks for self-monitoring, and SCT-based newsletters.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"* The training will involve the same frequency, duration, timeline, behavior change content, and interactions with behavioral coach as the GET Up PD program, and account for activity, social-contact, and attention.\n* Other components of the Stretching and Flexibility program include appropriate exercise equipment (yoga mat), one-on-one coaching sessions via Zoom, calendars, logbooks and newsletters similar to the GET Up PD program.",[15],[30],{"name":31,"affiliation":5,"role":32},"Robert Motl, PhD","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Brenda Jeng, PhD","CONTACT","312-996-6615","enrl@uic.edu",[40],{"facility":5,"status":25,"city":41,"state":42,"zip":43,"country":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Chicago","Illinois","60612","United States",{"type":46,"coordinates":47},"Point",[48,49],-87.65005,41.85003,{"lat":49,"lon":48},[52],{"name":31,"role":36,"phone":53,"phoneExt":25,"email":54},"312-413-0319","robmotl@uic.edu",{"type":32,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Robert W Motl","Professor",[59],{"name":60,"class":61},"National Institute on Aging (NIA)","NIH","100562426",false,"NCT06603012","Behavioral Intervention for Lifestyle Physical Activity in Parkinson's Disease","LifePD","Inclusion Criteria:\n\n* confirmed diagnosis of PD\n* Internet and email access\n* willingness to complete the cognitive assessments and questionnaires, wear the accelerometer, and undergo randomization\n* insufficient physical activity (i.e., not meeting current physical activity guidelines) based on a health contribution score of less than 14 units from the Godin Leisure-Time Exercise Questionnaire\n* self-reported ability to ambulate without assistance\n* age of 50+ years\n* English as a primary language\n* asymptomatic (i.e., one or fewer affirmatives on the Physical Activity Readiness Questionnaire \\[PAR-Q\\]) or physician approval for undertaking exercise training for those with 2 or more affirmatives on the PAR-Q\n\nExclusion Criteria:\n\n* above inclusion criteria not met\n* moderate or high risk of contraindications for possible injury or death when undertaking strenuous or maximal exercise using the PAR-Q\n* severe cognitive impairment that might preclude compliance with the conditions based on a modified Telephone Interview for Cognitive Status (TICS-M) score of less than 18\n* normal cognitive impairment based on the Montreal Cognitive Assessment (MoCA) score of 26 or more for avoiding ceiling effects involving change in cognitive function","ALL","50 Years",{"count":71,"type":72},50,"ESTIMATED","INTERVENTIONAL",[75],"NA","The investigators propose a Stage-I randomized controlled trial (RCT) of a remotely-delivered, 16-week social-cognitive theory-based behavioral intervention focusing on combined exercise (aerobic and resistance) training for yielding increases in device-measured physical activity and improvements in cognitive function, symptoms, and quality of life (QOL), and social-cognitive theory (SCT) outcomes among physically inactive persons with Parkinson's disease (PD). Participants (N=50) will be randomly assigned into exercise training (combined aerobic and resistance exercise) condition or active control (flexibility and stretching) condition. The 16-week intervention will be delivered and monitored remotely within a participant\\'s home\u002Fcommunity and supported by Zoom-based chats guided by SCT via a behavioral coach. Participants will receive training materials (e.g., prescriptive manual and exercise equipment), one-on-one coaching, action-planning via calendars, self-monitoring via logs, and SCT-based newsletters. The investigators hypothesize that the home-based exercise intervention will yield improvements in cognitive, symptomatic, and QOL outcomes.",[78],"Parkinson Disease (PD)",[80,81,82,83,84,85,86,87,88,89,90,91],"Parkinson disease","Parkinsonian disorders","Movement disorders","Basal ganglia diseases","Brain diseases","Nervous system diseases","Central nervous system diseases","Neurodegenerative diseases","Cognition","Walking","Exercise","Physical Activity","NOT_YET_RECRUITING","2026-06-02",{"date":95,"type":96},"2026-06-04","ACTUAL",{"date":98,"type":72},"2026-08",{"date":100,"type":72},"2027-08",{"name":5,"class":6},1]