[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100250950":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":28,"responsibleParty":50,"collaborators":10,"id":53,"slug":10,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":71,"overallStatus":43,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Beth Israel Deaconess Medical Center","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Infected Group",null,"subjects with suspected infection",{"label":13,"type":10,"description":14,"interventionNames":10},"Non-infected group","subjects without any infection",[16],{"name":17,"affiliation":5,"role":18},"Nathan Shapiro, MD MPH","PRINCIPAL_INVESTIGATOR",[20,24],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","617-754-2343","nshapiro@bidmc.harvard.edu",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"Carlo Ottanelli, BSc","617-650-0042","cottanel@bidmc.harvard.edu",[29,42],{"facility":30,"status":31,"city":32,"state":33,"zip":34,"country":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":10},"Massachusetts General Hospital","ACTIVE_NOT_RECRUITING","Boston","Massachusetts","02114","United States",{"type":37,"coordinates":38},"Point",[39,40],-71.05977,42.35843,{"lat":40,"lon":39},{"facility":5,"status":43,"city":32,"state":33,"zip":44,"country":35,"cosmosGeoPoint":45,"geoPoint":47,"contacts":48},"RECRUITING","02215",{"type":37,"coordinates":46},[39,40],{"lat":40,"lon":39},[49],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},{"type":18,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Nathan Shapiro","Professor of Emergency Medicine","100250950",false,"NCT02545478","Biomarkers in Infection","Early Detection of Inflammatory Biomarkers in Infection","Inclusion Criteria for Infected subjects:\n\n* Age 18 years of age or older\n* Confirmed or suspected infection\n\nInclusion Criteria for Control Subjects:\n\n* Age 18 years of age or older\n* A non-infectious clinical presentation to include\n* Normal white blood cell count ( \\> 4,000 and\u002For \\\u003C 12,000)\n* Normothermia ( \\> 96.5 and\u002For less 100.4)\n* Absence of the following clinical complaints: productive cough, fever, pyuria, rash\n* No evidence of acute coronary syndrome\n\nExclusion Criteria for Control Subjects:\n\n\\- Suspected infection",true,"ALL","18 Years",{"count":63,"type":64},4200,"ESTIMATED","OBSERVATIONAL","The purpose of this investigation is to evaluate how early biomarkers of infection and inflammation perform in identifying patients at risk for poor outcome in sepsis and septic shock.",[68,69,70],"Sepsis","Infection","Inflammation",[72,73,74,75,76],"septic shock","infection","inflammation","pathologic process","biomarkers","2026-04-13",{"date":79,"type":80},"2026-04-15","ACTUAL",{"date":82,"type":10},"2006-04",{"date":84,"type":64},"2031-12",{"name":5,"class":6},2]