[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100374820":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":32,"centralContacts":10,"locations":36,"responsibleParty":56,"collaborators":58,"id":62,"slug":10,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":10,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":10,"enrollmentInfo":70,"targetDuration":10,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":10,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"City of Hope Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Device feasibility (Macroduct Sweat Collection System)",null,"Patients undergo collection of sweat samples via Macroduct Sweat Collection System 3710S and saliva and blood samples within 24 hours after medication administrations. Patients also complete questionnaires over 5-10 minutes and have medical charts reviewed.",[13,14,15],"Procedure: Biospecimen Collection","Other: Medical Chart Review","Other: Questionnaire Administration",[17,22,28],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"PROCEDURE","Biospecimen Collection","Undergo collection of sweat, saliva, and blood samples",[9],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"Medical Chart Review","Review of medical chart",[9],[27],"Chart Review",{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"Questionnaire Administration","Complete questionnaire",[9],[33],{"name":34,"affiliation":5,"role":35},"Jeannine S McCune","PRINCIPAL_INVESTIGATOR",[37],{"facility":5,"status":38,"city":39,"state":40,"zip":41,"country":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Duarte","California","91010","United States",{"type":44,"coordinates":45},"Point",[46,47],-117.97729,34.13945,{"lat":47,"lon":46},[50,55],{"name":51,"role":52,"phone":53,"phoneExt":10,"email":54},"Jeannine S. McCune","CONTACT","626-218-4611","JMCCUNE@coh.org",{"name":51,"role":35,"phone":10,"phoneExt":10,"email":10},{"type":57,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[59],{"name":60,"class":61},"National Cancer Institute (NCI)","NIH","100374820",false,"NCT04160429","Biospecimen Analysis in Detecting Chemical Concentrations in Patients With Chronic or Infectious Diseases Receiving Meditations","Pilot Study to Evaluate Substances in Sweat, Saliva, and Blood","Inclusion Criteria:\n\n* Scheduled to receive medications including, but not limited to, cyclophosphamide, mycophenolic acid, mycophenolate mofetil, metformin or busulfan (any dose, any number of doses, any dosing frequency) as part of treatment at any time. Patients with chronic or infectious diseases can participate\n* Willingness to:\n\n  * Provide blood, sweat, and saliva samples\n  * Permit medical record review\n\nExclusion Criteria:\n\n* Pilocarpine allergy\n* Difficulty with understanding written English","ALL","18 Years",{"count":71,"type":72},100,"ESTIMATED","OBSERVATIONAL","This trial collects and analyzes sweat and saliva samples compared to blood in detecting chemical concentrations in the body in patients with chronic or infectious diseases receiving medications. Wearable sweat sensors are capable of monitoring electrolytes and metabolites (sodium, potassium, glucose, lactate, etc.) for health monitoring and disease diagnosis. Designing wearable sweat sensors capable of providing information regarding drug administration may be challenging due to ultralow concentrations in biofluids. This trial seeks to determine if the use of a smart wristband can accurately measure the levels of chemicals and substances in sweat.",[76,77],"Chronic Disease","Infectious Disorder","2025-11-06",{"date":80,"type":81},"2025-11-10","ACTUAL",{"date":83,"type":81},"2018-11-09",{"date":85,"type":72},"2029-07-30",{"name":5,"class":6},1]