[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100405041":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":40,"responsibleParty":94,"collaborators":98,"id":101,"slug":24,"hasResults":102,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":102,"sex":108,"minAge":109,"maxAge":110,"enrollmentInfo":111,"targetDuration":24,"studyType":114,"phases":115,"briefSummary":117,"conditions":118,"keywords":24,"overallStatus":43,"whyStopped":24,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":132},{"fullName":5,"class":6},"University of Kentucky","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Physical Therapy with Sham BFRT","ACTIVE_COMPARATOR","Participants will undergo 8 weeks of sham blood flow restriction training with cuff inflated to less than 10% occlusion.",[13],"Device: Sham Blood Flow Restriction Training",{"label":15,"type":10,"description":16,"interventionNames":17},"Standard Physical Therapy with BFRT","Participants will undergo 8 weeks of blood flow restriction training with cuff inflated to 60% occlusion.",[18],"Device: Blood Flow Restriction Training",[20,25],{"type":21,"name":22,"description":16,"armGroupLabels":23,"otherNames":24},"DEVICE","Blood Flow Restriction Training",[15],null,{"type":21,"name":26,"description":11,"armGroupLabels":27,"otherNames":24},"Sham Blood Flow Restriction Training",[9],[29],{"name":30,"affiliation":5,"role":31},"Caitlin Conley, PhD","STUDY_DIRECTOR",[33,37],{"name":30,"role":34,"phone":35,"phoneExt":24,"email":36},"CONTACT","8592571939","caitlin.conley2@uky.edu",{"name":38,"role":34,"phone":24,"phoneExt":24,"email":39},"Natalie Corey","natalie.corey@uky.edu",[41,57,68,83],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"UK Healthcare at Turfland","RECRUITING","Lexington","Kentucky","40504","United States",{"type":49,"coordinates":50},"Point",[51,52],-84.47772,37.98869,{"lat":52,"lon":51},[55],{"name":30,"role":34,"phone":56,"phoneExt":24,"email":36},"859-257-1939",{"facility":58,"status":43,"city":44,"state":45,"zip":59,"country":47,"cosmosGeoPoint":60,"geoPoint":62,"contacts":63},"University of Kentucky Biomotion Laboratory","40536",{"type":49,"coordinates":61},[51,52],{"lat":52,"lon":51},[64],{"name":65,"role":34,"phone":66,"phoneExt":24,"email":67},"Brian Noehren, PhD, PT","8592180581","b.noehren@uky.edu",{"facility":69,"status":43,"city":70,"state":71,"zip":72,"country":47,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"Center for Sports Performance and Research","Foxborough","Massachusetts","02035",{"type":49,"coordinates":74},[75,76],-71.24783,42.06538,{"lat":76,"lon":75},[79],{"name":80,"role":34,"phone":81,"phoneExt":24,"email":82},"Molly Zgoda","508-216-1145","mzgoda@mgb.org",{"facility":84,"status":43,"city":70,"state":71,"zip":72,"country":47,"cosmosGeoPoint":85,"geoPoint":87,"contacts":88},"Foxboro Sports Medicine Clinic",{"type":49,"coordinates":86},[75,76],{"lat":76,"lon":75},[89,93],{"name":90,"role":34,"phone":91,"phoneExt":24,"email":92},"Cale Jacobs, PhD","508-216-1145.","cjacobs@bwh.harvard.edu",{"name":80,"role":34,"phone":91,"phoneExt":24,"email":82},{"type":95,"investigatorFullName":96,"investigatorTitle":97,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","Caitlin Conley","Assistant Professor",[99],{"name":100,"class":6},"The Cleveland Clinic","100405041",false,"NCT04554212","Blood Flow Restriction Training After Patellar INStability","Blood Flow Restriction Training After Patellar INStability (BRAINS Trial)","BRAINS","Inclusion Criteria:\n\n* Diagnosis of traumatic patellar instability (either primary or recurrent) determined by an American Board of Family Medicine certified physician with a Certificate of Added Qualifications in Sports Medicine or licensed Physical Therapist utilizing clinical examination, radiographic imaging, and patients' reports of instability\n* Age 14 to 40 years\n* Skeletally mature with closed growth plates visualized by radiograph\n* A score of 80 or more on the Sports Activity Scale, which corresponds to participating in \"running, twisting, turning (tennis, racquetball, handball, ice hockey, field hockey, skiing, wrestling)\" at least 1-3 times per week\n* Desire to resume pre-injury activity level\n\nExclusion Criteria:\n\n* Concomitant osteochondral lesion requiring surgical fixation\n* Radiographic evidence of osteoarthritis (\\\u003C Kellgren-Lawrence Grade 2)\n* Previous ipsilateral or contralateral knee surgery\n* Most recent instability event more than 3 months before enrollment\n* History of any inflammatory disorder\n* BMI \\> 35 kg\u002Fm2\n* Diabetes or uncontrolled hypertension\n* Varicose veins or a history of personal or immediate family history (parental or sibling) of deep vein thrombosis\n* Pre-existing conditions or previous surgeries that effect the ability to walk\n* Planned trips or vacations that will result in the inability to attend 4 consecutive physical therapy sessions","ALL","14 Years","40 Years",{"count":112,"type":113},78,"ESTIMATED","INTERVENTIONAL",[116],"NA","This research study is designed to allow health care professionals and researchers to answer many questions about whether a new type of physical therapy called blood flow restriction training (called BFRT) will improve recovery for those with patellar instability.",[119,120,121,122],"Patellar Dislocation","Knee Injuries","Leg Injury","Wounds and Injuries","2025-07-02",{"date":125,"type":126},"2025-07-03","ACTUAL",{"date":128,"type":126},"2020-09-09",{"date":130,"type":113},"2026-06-30",{"name":96,"class":6},4]