[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552361":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":35,"locations":43,"responsibleParty":92,"collaborators":95,"id":99,"slug":25,"hasResults":100,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":9,"eligibilityCriteria":104,"healthyVolunteers":100,"sex":105,"minAge":106,"maxAge":25,"enrollmentInfo":107,"targetDuration":25,"studyType":110,"phases":111,"briefSummary":113,"conditions":114,"keywords":117,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":131},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"BMT-CARE","EXPERIMENTAL","Participants randomized to BMT-CARE plus usual care will complete the following:\n\n* Questionnaires at baseline, and days 60, 90 and 180 post HCT.\n* Receive the BMT-CARE intervention from enrollment up to 60 days post-HCT. BMT-CARE is a -6-session caregiver-directed cognitive behavioral therapy (CBT)-based psychosocial intervention that integrates HCT-related education with CBT strategies to enhance caregiver knowledge and skills.\n* Receive usual care as per HCT practice which entails meeting a transplant social worker prior to HCT and as needed for extra visits.",[13],"Behavioral: BMT-CARE",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care","ACTIVE_COMPARATOR","Participants randomized to usual care will complete the following\n\n* Questionnaires at baseline, and days 60, 90 and 180 post HCT.\n* Receive usual care as per HCT practice which entails meeting a transplant social worker prior to HCT and as needed for extra visits.",[19],"Behavioral: Usual Care",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Therapist-delivered psychosocial intervention comprised of 6 sessions",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Meeting a transplant social worker prior to HCT and as needed for extra visits",[15],[30,33],{"name":31,"affiliation":5,"role":32},"Areej El-Jawahri, MD","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":5,"role":32},"Jamie Jacobs, PhD",[36,40],{"name":31,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","617-721-4000","ael-jawahri@mgb.org",{"name":34,"role":37,"phone":41,"phoneExt":25,"email":42},"617-724-4000","jjacobs@mgh.harvard.edu",[44,62,77],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"University of Alabama at Brimingham","RECRUITING","Birmingham","Alabama","35294","United States",{"type":52,"coordinates":53},"Point",[54,55],-86.80249,33.52066,{"lat":55,"lon":54},[58],{"name":59,"role":37,"phone":60,"phoneExt":25,"email":61},"James Dionne-Odom","205-934-7597","dionneod@uab.edu",{"facility":63,"status":46,"city":64,"state":65,"zip":66,"country":50,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"Moffitt Cancer Center","Tampa","Florida","33612",{"type":52,"coordinates":68},[69,70],-82.45843,27.94752,{"lat":70,"lon":69},[73],{"name":74,"role":37,"phone":75,"phoneExt":25,"email":76},"Heather Jim","813-745-6369","heather.jim@moffitt.org",{"facility":78,"status":46,"city":79,"state":80,"zip":81,"country":50,"cosmosGeoPoint":82,"geoPoint":86,"contacts":87},"Massachusetts General Hospital Cancer Center","Boston","Massachusetts","02114",{"type":52,"coordinates":83},[84,85],-71.05977,42.35843,{"lat":85,"lon":84},[88,91],{"name":31,"role":37,"phone":89,"phoneExt":25,"email":90},"617-643-4003","AEL-JAWAHRI@PARTNERS.ORG",{"name":31,"role":32,"phone":25,"phoneExt":25,"email":25},{"type":32,"investigatorFullName":93,"investigatorTitle":94,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"El-Jawahri, Areej,M.D.","Associate Professor of Medicine",[96],{"name":97,"class":98},"National Institutes of Health (NIH)","NIH","100552361",false,"NCT06472089","BMT-CARE: Psychosocial Intervention for Transplant Caregivers","Multimodal Psychosocial Intervention for Caregivers of Patients Undergoing Hematopoietic Stem Cell Transplantation","Caregiver Inclusion Criteria:\n\n* Adult caregivers (≥18 years) relative or friend of a patient identified as living with them or having in-person contact with them at least twice a week.\n* Caregiver of a patient receiving allogeneic or autologous HCT for the treatment of cancer.\n* Ability to read and respond to survey questions in English, Spanish or with minimal assistance from an interpreter.\n\nCaregiver Exclusion Criteria:\n\n* Caregivers of patients undergoing HCT for a benign hematologic condition or undergoing outpatient HCT.\n* Caregivers with a major untreated psychiatric or cognitive condition which the treating oncology clinicians believes interferes with the capacity to provide informed consent.\n* Caregivers of patients who have already undergone HCT within the past 5 years\n\nPatient Inclusion Criteria:\n\n* Adult patients (≥18 years) with a hematologic malignancy and planned admission for autologous or allogeneic HCT.\n* Ability to respond to questions in English, Spanish, or with minimal assistance from an interpreter.","ALL","18 Years",{"count":108,"type":109},800,"ESTIMATED","INTERVENTIONAL",[112],"NA","The goal of this study is to evaluate whether a psychological intervention (BMT-CARE) is effective at improving the quality of life in caregivers and patients treated with hematopoietic cell transplant compared to usual care, and to identify critical facilitators and barriers for BMT-CARE implementation and adoption.",[115,116],"Bone Marrow Transplant Complications","Hematologic Malignancy",[118,119,120,121],"Neoplasms by Site","Hematologic Diseases","Neoplasms","Hematologic Neoplasms","2025-10-13",{"date":124,"type":125},"2025-10-15","ACTUAL",{"date":127,"type":125},"2025-01-10",{"date":129,"type":109},"2029-02",{"name":5,"class":6},3]