[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100477967":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":34,"responsibleParty":63,"collaborators":18,"id":66,"slug":18,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":72,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":18,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":18,"overallStatus":37,"whyStopped":18,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Guangzhou Women and Children's Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Proactive management during pregnancy","EXPERIMENTAL","A combination of dietary, physical activity and lifestyle modification.",[13],"Behavioral: Lifestyle modification",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Care","NO_INTERVENTION","No additional intervention beyond standard care procedure.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Lifestyle modification","This lifestyle modification aiming to provide proactive health management during pregnancy, which contains the following: 1) balanced dietary intake based on the Chinese Dietary Guideline; 2) sufficient physical activity; 3) changes in lifestyles (e.g. sleep, sun exposure etc.)",[9],[26,31],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Qiu Qiu, Dr.","CONTACT","86+02038367159","qxiu0161@163.com",{"name":32,"role":28,"phone":33,"phoneExt":18,"email":18},"Songying Shen, Msc.","86+02038367160",[35,50],{"facility":36,"status":37,"city":38,"state":18,"zip":18,"country":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Fuying Campus, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China","RECRUITING","Guangzhou","China",{"type":41,"coordinates":42},"Point",[43,44],113.25,23.11667,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":49,"phoneExt":18,"email":30},"Xiu Qiu","086-020-38367160",{"facility":51,"status":37,"city":38,"state":18,"zip":18,"country":39,"cosmosGeoPoint":52,"geoPoint":54,"contacts":55},"Zhujiang new town campus, Guangzhou Women and Children's Medical Center, China",{"type":41,"coordinates":53},[43,44],{"lat":44,"lon":43},[56,60],{"name":57,"role":28,"phone":58,"phoneExt":18,"email":59},"Xiu Qiu, MD,PhD","86-020-38367160","xiu.qiu@bigcs.org",{"name":61,"role":28,"phone":58,"phoneExt":18,"email":62},"Jian-Rong He, MD, PhD","jianrong.he@bigcs.org",{"type":64,"investigatorFullName":48,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Director of the Department of Women's Health","100477967",false,"NCT05503849","Born In Guangzhou Intervention Study","BIGIS","Inclusion Criteria:\n\n* Pregnant women attending prenatal care at Guangzhou Women and Children's Medical Center (GWCMC) \\\u003C20 weeks' gestation\n* Pregnant women plan to deliver at GWCMC\n* Pregnant women intend to reside in Guangzhou for at least 3 years\n\nExclusion Criteria:\n\n* Multiple pregnancies\n* Existing medical conditions (uncontrolled diabetes, hypertension or thyroid disease; other serious cardiovascular diseases, respiratory or systematic disorders)\n* Use of drugs (aspirin, metformin, low molecular weight heparin)\n* Women with reading and\u002For writing difficulties\n* Women with serious mental disorders\n* Women with eating disorders",true,"FEMALE","18 Years","50 Years",{"count":77,"type":78},1160,"ESTIMATED","INTERVENTIONAL",[81],"NA","The main objective of this study is to test the efficacy of an intervention package (dietary, physical and lifestyle modification) during pregnancy in improving the clinical outcomes of mother-infant dyads.",[84,85,86],"Pregnancy Outcomes","Child Development","Pregnancy Complications","2025-04-07",{"date":89,"type":90},"2025-04-10","ACTUAL",{"date":92,"type":90},"2024-07-22",{"date":94,"type":78},"2032-09",{"name":5,"class":6},2]