[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100501596":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":31,"responsibleParty":54,"collaborators":10,"id":56,"slug":10,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":10,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":10,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Cohort 1-individuals who are naïve to SCS",null,"Individuals with chronic neuropathic pain who are naïve to SCS and were selected for SCS trial period as part of their clinical care will participate in two study visits: before the beginning of the SCS trial and the end of the trial period. Data collection will be consistent across all data collection timepoints (T1 - T3) and include rs-fNIRS\u002FEEG and clinical pain measures.",{"label":13,"type":10,"description":14,"interventionNames":10},"Cohort 2-individuals with effective implanted SCS 6 months","Cohort 2: Participants with effective implanted SCS 6 months will participate in three study visits conducted 24-48 hours apart. Data will be collected during SCS use and following an SCS washout period. Data collection will be consistent across all data collection timepoints(T1-T4) and include rs-fNIRS\u002FEEG and clinical pain measures. Both cohorts will receive paresthesia based SCS.",[16],{"name":17,"affiliation":18,"role":19},"Svetlana Pundik, MD","Louis Stokes VA Medical Center, Cleveland, OH","PRINCIPAL_INVESTIGATOR",[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Cheryl Dudek","CONTACT","(216) 679-3800","cheryl.dudek@va.gov",{"name":27,"role":23,"phone":28,"phoneExt":29,"email":30},"Holly B Henry","(216) 791-3800","64657","holly.henry@va.gov",[32],{"facility":18,"status":33,"city":34,"state":35,"zip":36,"country":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Cleveland","Ohio","44106-1702","United States",{"type":39,"coordinates":40},"Point",[41,42],-81.69541,41.4995,{"lat":42,"lon":41},[45,50,53],{"name":46,"role":23,"phone":47,"phoneExt":48,"email":49},"Jessica P McCabe, MPT DPT","216-791-3800","4691","Jessica.Mccabe@va.gov",{"name":17,"role":23,"phone":28,"phoneExt":51,"email":52},"3732","svetlana.pundik@va.gov",{"name":17,"role":19,"phone":10,"phoneExt":10,"email":10},{"type":55,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100501596",false,"NCT05811312","Brain Connectivity Changes With Spinal Cord Stimulation and Treatment of Chronic Pain: A Resting State NIRS\u002FEEG Study","Brain Connectivity Changes With Spinal Cord Stimulation Treatment of Chronic Pain: A Resting State NIRS\u002FEEG Study","Inclusion Criteria:\n\n* 18 years of age and a US veteran\n* Diagnosis of chronic neuropathic pain.\n* Current patient at Cleveland VA Medical Center receiving care via Pain Medicine Center.\n* Current user of tonic parasthesia-based SCS (pain relief 50% according to NPRS) or undergoing trial SCS period as part of clinical care.\n* Able to provide informed consent.\n* Medically and psychologically stable.\n\nExclusion Criteria:\n\n* Metal in the skull or deformity of the skull\n* Pregnancy or pregnancy planning during the study period.\n* Unable to provide informed consent.","ALL","18 Years",{"count":65,"type":66},40,"ESTIMATED","OBSERVATIONAL","This study aims to assess how use of spinal cord stimulation for the treatment of chronic pain impacts brain structure and function. The investigators will use a non-invasive neuroimaging technique called resting state Near Infrared Spectroscopy and Electroencephalography (rs-fNIRS\u002FEEG). The investigators will enroll Veterans who are currently receiving care at the Medical Center and who are either long term users of SCS for the treatment of their chronic pain or being evaluated for use of SCS to treat their pain.",[70],"Neuropathic Pain",[72,73,74,75,76],"chronic pain","neuropathic pain","spinal cord stimulation","fNIRS","electroencephalography","2026-05-27",{"date":79,"type":80},"2026-06-01","ACTUAL",{"date":82,"type":80},"2023-07-01",{"date":84,"type":66},"2027-06-30",{"name":5,"class":6},1]