[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616641":3},{"organization":4,"outcomesModule":7,"designInfo":21,"detailedDescription":23,"studyPopulation":24,"armGroups":20,"interventions":25,"overallOfficials":20,"centralContacts":29,"locations":20,"responsibleParty":39,"collaborators":20,"id":41,"slug":20,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":20,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":20,"studyType":53,"phases":20,"briefSummary":54,"conditions":55,"keywords":20,"overallStatus":57,"whyStopped":20,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":20},{"fullName":5,"class":6},"The Fourth Affiliated Hospital of Zhejiang University School of Medicine","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":20},[9,13],{"measure":10,"description":11,"timeFrame":12},"VAS","The Visual Analogue Scale (VAS) was used to assess the severity of low back pain, with 0 indicating no pain and 10 indicating unbearable severe pain.","After 4 weeks of treatment",{"measure":14,"description":15,"timeFrame":12},"JOA","The Japanese Orthopaedic Association (JOA) efficacy assessment criteria for low back disorders were applied to evaluate lumbar function.",[17],{"measure":18,"description":19,"timeFrame":12},"MRI","Magnetic resonance imaging was used to assess the effects of treatment on brain networks.",null,{"allocation":20,"interventionModel":20,"interventionModelDescription":20,"primaryPurpose":20,"observationalModel":6,"timePerspective":22,"maskingInfo":20},"PROSPECTIVE","This phase of the research aims to elucidate the neuroplasticity mechanisms induced by CNLBP treatment, providing a theoretical basis for the future development of personalized rehabilitation protocols based on brain network subtypes, ultimately achieving the clinical goals of reducing pain recurrence rates and improving long-term prognosis in patients.","All patients were assigned numbers from 1 to 40. Starting at any row and column in a random number table, 40 random numbers were sequentially recorded in correspondence with the patient numbers. The random numbers were then ranked in ascending order, with ranks 1-20 assigned to the experimental group and ranks 21-40 to the control group. All patients continued to receive conventional treatment and comprehensive rehabilitation therapy.",[26],{"type":6,"name":27,"description":28,"armGroupLabels":20,"otherNames":20},"Multimodal Imaging Evaluation","Functional connectivity analysis of brain networks based on functional magnetic resonance imaging (fMRI) technology",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":20,"email":34},"yongxiang li","CONTACT","15267370425","8017074@zju.edu.cn",{"name":36,"role":32,"phone":37,"phoneExt":20,"email":38},"yali liu","15988537921","8017039@zju.edu.cn",{"type":40,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100616641",false,"NCT07308249","Brain Network fMRI Analysis in Proprioceptive Training for Chronic Low Back Pain","Research on the Application of Brain Network Functional Connectivity Analysis Based on Functional Magnetic Resonance Imaging in Proprioceptive Training for Chronic Non-Specific Low Back Pain","Inclusion Criteria:\n\n* Age between 18 and 60 years old;\n\n  * Current or past low back pain lasting more than three months; ③ No abnormal sensation or reflex abnormalities in the lower limbs; ④ Able to commit to participating in training three times per week for three months.\n\nExclusion Criteria:\n\n* Fractures, dislocations, structural abnormalities, prior surgery, metal implants, or lumbar disc herniation;\n\n  * Comorbidities such as severe cardiovascular diseases, neurological disorders, osteoporosis, or metabolic diseases; ③ Low back pain caused by visceral diseases;\n\n    * VAS score (range 1-10) exceeding 8 points;\n\n      * Pregnant or lactating women; ⑥ Symptoms of nerve root irritation; ⑦ Recent participation in core stability training.","ALL","18 Years","60 Years",{"count":51,"type":52},40,"ESTIMATED","OBSERVATIONAL","Through longitudinal analysis of dynamic changes in DMN functional connectivity before and after sensory training intervention, combined with pain behavioral and functional improvement indicators, this study systematically reveals the central neural remodeling patterns in CNLBP and establishes an objective efficacy evaluation system based on multimodal imaging.",[56],"Brain Network Functional Connectivity","NOT_YET_RECRUITING","2025-12-15",{"date":60,"type":61},"2025-12-29","ACTUAL",{"date":63,"type":52},"2025-12-20",{"date":65,"type":52},"2028-12-30",{"name":5,"class":6}]