About this trial

This study investigates the computational mechanisms associated with psychiatric disease dimensions. The study will characterize the relationship between computational parameter estimates of task performance and psychiatric symptoms and diagnoses with a longitudinal approach over a 12 month interval. Participants will be healthy participants recruited through Prolific an on-line crowdsourcing service, and psychiatric patients and healthy participants recruited via UCLA Psychiatry Clinics and UCLA's STAND Program

Eligibility criteria

Qualifiers

Age range of 18 to 65.

Not currently having a psychiatric diagnosis determined after psychiatric evaluation by Drs. Tadayon-Nejad and Wei (both are board certified psychiatrists).

Ability to understand and perform experimental tasks, i.e. basic ability to communicate and comprehend tasks.

Ability to give informed consent.

Disqualifiers

Age range of 18 to 65.

Psychiatric diagnosis of any type of depressive disorders, any type of anxiety disorders or obsessive-compulsive disorder.

Primary or comorbid bipolar disorders are allowed but only if not in the acute manic phase.

Comorbidity with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are allowed.

Trial design

Treatments tested in this trial

  • Behavioral task performance

Treatment groups

1,100 Participants
are divided into 1 treatment group

Locations

2
UCLA Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles90095, Los AngelesCalifornia, United States
California Insitute of Technology91125, PasadenaCalifornia, United States

Sponsors and collaborators

California Institute of Technology

Lead sponsor