About this trial

This multicenter, prospective cohort study evaluates early cardiac dysfunction in adult survivors of childhood cancer. The hypothesis of this study is that cardiac dysfunction can be detected earlier when using speckle tracking echocardiography as novel echocardiographic technique compared to conventional echocardiography.

Eligibility criteria

Qualifiers

Registered in the ChCR

Formerly treated at the Department of Pediatric Hematology/Oncology of one of five participating centers

Treated with any chemotherapy and/or chest radiation

Survived ≥ 5 years since most recent cancer diagnosis (primary cancer, relapse(s), secondary cancer) at time of examination

Disqualifiers

Study participants will be excluded if they do not meet the above mentioned inclusion criteria or refuse to participate in the study.

Trial design

Treatments tested in this trial

  • cardiac assessment

Treatment groups

No treatment groups listed

Locations

6
Department of Cardiology, University Hospital Basel4031, BaselCanton of Basel-City, Switzerland
Institute of Social and Preventive Medicine, University of Bern3012, BernCanton of Bern, Switzerland
Department of Cardiology, Inselspital Bern3010, Bern Switzerland
Department of Cardiology, University Hospitals of Geneva1205, Geneva Switzerland

Sponsors and collaborators

University of Bern

Lead sponsor

University Hospital, Basel, Switzerland

Collaborator

Insel Gruppe AG, University Hospital Bern

Collaborator

Cantonal Hospital of St. Gallen

Collaborator

Luzerner Kantonsspital

Collaborator

University Hospital, Geneva

Collaborator

University Children's Hospital Basel

Collaborator