[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100414889":3},{"organization":4,"outcomesModule":7,"designInfo":26,"detailedDescription":28,"studyPopulation":29,"armGroups":30,"interventions":38,"overallOfficials":53,"centralContacts":67,"locations":73,"responsibleParty":289,"collaborators":291,"id":301,"slug":25,"hasResults":302,"nctId":303,"briefTitle":304,"officialTitle":304,"acronym":305,"eligibilityCriteria":306,"healthyVolunteers":302,"sex":307,"minAge":308,"maxAge":25,"enrollmentInfo":309,"targetDuration":312,"studyType":313,"phases":25,"briefSummary":314,"conditions":315,"keywords":317,"overallStatus":76,"whyStopped":25,"lastUpdateSubmitDate":325,"lastUpdatePostDateStruct":326,"startDateStruct":329,"completionDateStruct":331,"leadSponsor":333,"locationsCount":334},{"fullName":5,"class":6},"Tufts Medical Center","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":15,"otherOutcomes":25},[9,13],{"measure":10,"description":11,"timeFrame":12},"Rate of Mortality","Death in subjects during the time frame.","30 days after discharge",{"measure":10,"description":11,"timeFrame":14},"1 year after discharge",[16,20,21,24],{"measure":17,"description":18,"timeFrame":19},"Rate of Re-hospitalization","We will be observing if patient was hospitalized again during the 1 year-time frame. We will collect information on surgeries and interventions during the course of rehospitalization.","30 day after discharge",{"measure":17,"description":18,"timeFrame":14},{"measure":22,"description":23,"timeFrame":19},"New York Heart Association (NYHA) Class","NYHA Classification provides a way to classify the stages of heart failure. Class I- No symptoms and no limitation in ordinary physical activity Class II- Mild symptoms (mild shortness of breath and\u002For angina) and slight limitation during ordinary activity Class III - Marked limitation in activity due to symptoms, even during less-than-ordinary activity Class IV - Severe limitations",{"measure":22,"description":23,"timeFrame":14},null,{"allocation":25,"interventionModel":25,"interventionModelDescription":25,"primaryPurpose":25,"observationalModel":27,"timePerspective":6,"maskingInfo":25},"COHORT","The Cardiogenic Shock Working Group is an Academic Research Consortium involving multiple medical centers within the United States and includes a multicenter registry for patients with cardiogenic shock. De-identified clinical variables are collected from medical records and follow-up phone calls. There is currently no central database for cardiogenic shock, therefore analysis of cardiogenic shock on a larger scale is limited. A goal of the Cardiogenic Shock Working Group is to create a centralized registry, compiled of data from multiple institutions, to analyze clinical outcomes. The Cardiogenic Shock Working Group Registry will include a retrospective arm, where data is collected during the course of the hospital stay, and a prospective arm, where long-term outcomes will be assessed.","People who are 18 or older who have an official diagnosis of cardiogenic shock.",[31],{"label":32,"type":25,"description":33,"interventionNames":34},"Cardiogenic Shock Patients","Cardiogenic Shock patients eligible for this study are defined by at least one of the two categories below.\n\n1. Patients have at least 2 of the following concurrently at any point during the index hospitalization: MAP \\\u003C 60mmHg or a \\>30mmHg drop in MAP from baseline, SBP \\\u003C 90mmHg or a \\>30mmHg drop in SBP from baseline, Pulse \\> 100, Cardiac Index \\\u003C 2.2, Cardiac Power Output ≤ 0.6 or PAPI \\\u003C 1.0.\n2. Patients require the use of at least 1 vasopressor, inotrope or acute mechanical circulatory support device to maintain values above the above targets.",[35,36,37],"Drug: Vasopressor","Drug: Inotrope","Device: Acute Mechanical Circulatory Support Devices",[39,44,48],{"type":40,"name":41,"description":42,"armGroupLabels":43,"otherNames":25},"DRUG","Vasopressor","The vasopressors include phenylephrine, norepinephrine, epinephrine, dopamine and vasopressin.",[32],{"type":40,"name":45,"description":46,"armGroupLabels":47,"otherNames":25},"Inotrope","Inotropes include dobutamine and milrinone.",[32],{"type":49,"name":50,"description":51,"armGroupLabels":52,"otherNames":25},"DEVICE","Acute Mechanical Circulatory Support Devices","Acute Mechanical Circulatory Support devices include ECMO (VV), ECMO (VA), Impella CP, Impella 2.5, Impella 5.0, Impella 5.5, Impella RP, IABP, Centrimag, Tandem Heart and ProTek Duo.",[32],[54,58,61,64],{"name":55,"affiliation":56,"role":57},"Reshad Garan, MD","Beth Israel Deaconess Medical Center","STUDY_DIRECTOR",{"name":59,"affiliation":60,"role":57},"Claudius Mahr, DO","University of Washington",{"name":62,"affiliation":63,"role":57},"Jaime Hernandez-Montfort, MD","Cleveland Clinic Foundation-Florida",{"name":65,"affiliation":66,"role":57},"Daniel Burkhoff, MD PhD","CardioVascular Research Foundation",[68],{"name":69,"role":70,"phone":71,"phoneExt":25,"email":72},"Navin K Kapur, MD","CONTACT","6176368252","nkapur@tuftsmedicalcenter.org",[74,93,108,118,132,146,156,170,183,196,210,220,234,248,262,276],{"facility":75,"status":76,"city":77,"state":78,"zip":79,"country":80,"countryCode":81,"cosmosGeoPoint":82,"geoPoint":87,"contacts":88},"Cleveland Clinic Florida","RECRUITING","Weston","Florida","33331","United States","US",{"type":83,"coordinates":84},"Point",[85,86],-80.39977,26.10037,{"lat":86,"lon":85},[89,91],{"name":90,"role":70,"phone":25,"phoneExt":25,"email":25},"Jaime Hernandez-Montfort, MD MPH",{"name":90,"role":92,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"facility":94,"status":76,"city":95,"state":96,"zip":97,"country":80,"countryCode":81,"cosmosGeoPoint":98,"geoPoint":102,"contacts":103},"Northwestern Medicine","Chicago","Illinois","60611",{"type":83,"coordinates":99},[100,101],-87.65005,41.85003,{"lat":101,"lon":100},[104,106],{"name":105,"role":70,"phone":25,"phoneExt":25,"email":25},"Esther Vorovich, MD",{"name":107,"role":92,"phone":25,"phoneExt":25,"email":25},"Esther Vorovich",{"facility":109,"status":76,"city":95,"state":96,"zip":110,"country":80,"countryCode":81,"cosmosGeoPoint":111,"geoPoint":113,"contacts":114},"University of Chicago","60612",{"type":83,"coordinates":112},[100,101],{"lat":101,"lon":100},[115,117],{"name":116,"role":70,"phone":25,"phoneExt":25,"email":25},"Sandeep Nathan, MD",{"name":116,"role":92,"phone":25,"phoneExt":25,"email":25},{"facility":119,"status":76,"city":120,"state":121,"zip":122,"country":80,"countryCode":81,"cosmosGeoPoint":123,"geoPoint":127,"contacts":128},"Maine Medical Center","Portland","Maine","04102",{"type":83,"coordinates":124},[125,126],-70.2589,43.65737,{"lat":126,"lon":125},[129,131],{"name":130,"role":70,"phone":25,"phoneExt":25,"email":25},"Andrew Schwartzman, MD",{"name":130,"role":92,"phone":25,"phoneExt":25,"email":25},{"facility":5,"status":76,"city":133,"state":134,"zip":135,"country":80,"countryCode":81,"cosmosGeoPoint":136,"geoPoint":140,"contacts":141},"Boston","Massachusetts","02111",{"type":83,"coordinates":137},[138,139],-71.05977,42.35843,{"lat":139,"lon":138},[142,144],{"name":69,"role":70,"phone":143,"phoneExt":25,"email":72},"6176366140",{"name":145,"role":92,"phone":25,"phoneExt":25,"email":25},"Navin Kapur, MD",{"facility":56,"status":76,"city":133,"state":134,"zip":147,"country":80,"countryCode":81,"cosmosGeoPoint":148,"geoPoint":150,"contacts":151},"02215",{"type":83,"coordinates":149},[138,139],{"lat":139,"lon":138},[152,154],{"name":153,"role":70,"phone":25,"phoneExt":25,"email":25},"Arthur R Garan",{"name":155,"role":92,"phone":25,"phoneExt":25,"email":25},"Arthur R Garan, MD",{"facility":157,"status":76,"city":158,"state":159,"zip":160,"country":80,"countryCode":81,"cosmosGeoPoint":161,"geoPoint":165,"contacts":166},"Hackensack Meridian Health","Hackensack","New Jersey","07601",{"type":83,"coordinates":162},[163,164],-74.04347,40.88593,{"lat":164,"lon":163},[167,169],{"name":168,"role":70,"phone":25,"phoneExt":25,"email":25},"Haroon Faraz, MD",{"name":168,"role":92,"phone":25,"phoneExt":25,"email":25},{"facility":171,"status":76,"city":172,"state":172,"zip":173,"country":80,"countryCode":81,"cosmosGeoPoint":174,"geoPoint":178,"contacts":179},"Columbia University Irving Medical Center","New York","10032",{"type":83,"coordinates":175},[176,177],-74.00597,40.71427,{"lat":177,"lon":176},[180,182],{"name":181,"role":70,"phone":25,"phoneExt":25,"email":25},"Justin Fried, MD",{"name":181,"role":92,"phone":25,"phoneExt":25,"email":25},{"facility":184,"status":76,"city":120,"state":185,"zip":186,"country":80,"countryCode":81,"cosmosGeoPoint":187,"geoPoint":191,"contacts":192},"Providence St. Vincent Heart Clinic","Oregon","97225",{"type":83,"coordinates":188},[189,190],-122.67621,45.52345,{"lat":190,"lon":189},[193,195],{"name":194,"role":70,"phone":25,"phoneExt":25,"email":25},"Jacob Abraham, MD",{"name":194,"role":92,"phone":25,"phoneExt":25,"email":25},{"facility":197,"status":76,"city":198,"state":199,"zip":200,"country":80,"countryCode":81,"cosmosGeoPoint":201,"geoPoint":205,"contacts":206},"Allegheny General Hospital","Pittsburgh","Pennsylvania","15212",{"type":83,"coordinates":202},[203,204],-79.99589,40.44062,{"lat":204,"lon":203},[207,209],{"name":208,"role":70,"phone":25,"phoneExt":25,"email":25},"Manreet Kanwar, MD",{"name":208,"role":92,"phone":25,"phoneExt":25,"email":25},{"facility":211,"status":76,"city":198,"state":199,"zip":212,"country":80,"countryCode":81,"cosmosGeoPoint":213,"geoPoint":215,"contacts":216},"University Of Pittsburgh Medical Center","15261",{"type":83,"coordinates":214},[203,204],{"lat":204,"lon":203},[217,219],{"name":218,"role":70,"phone":25,"phoneExt":25,"email":25},"Gavin Hickey, MD",{"name":218,"role":92,"phone":25,"phoneExt":25,"email":25},{"facility":221,"status":76,"city":222,"state":223,"zip":224,"country":80,"countryCode":81,"cosmosGeoPoint":225,"geoPoint":229,"contacts":230},"Baylor Scott & White Advanced Heart Failure Clinic","Dallas","Texas","75201",{"type":83,"coordinates":226},[227,228],-96.80667,32.78306,{"lat":228,"lon":227},[231,233],{"name":232,"role":70,"phone":25,"phoneExt":25,"email":25},"Detlef Wencker, MD",{"name":232,"role":92,"phone":25,"phoneExt":25,"email":25},{"facility":235,"status":76,"city":236,"state":223,"zip":237,"country":80,"countryCode":81,"cosmosGeoPoint":238,"geoPoint":242,"contacts":243},"University of Texas Medical Branch","Galveston","77555",{"type":83,"coordinates":239},[240,241],-94.7977,29.30135,{"lat":241,"lon":240},[244,246],{"name":245,"role":70,"phone":25,"phoneExt":25,"email":25},"Wissam Khalife, MD",{"name":247,"role":70,"phone":25,"phoneExt":25,"email":25},"Wissam Khalife",{"facility":249,"status":76,"city":250,"state":223,"zip":251,"country":80,"countryCode":81,"cosmosGeoPoint":252,"geoPoint":256,"contacts":257},"Houston Methodist Hospital","Houston","77030",{"type":83,"coordinates":253},[254,255],-95.36327,29.76328,{"lat":255,"lon":254},[258,260],{"name":259,"role":70,"phone":25,"phoneExt":25,"email":25},": Ju H Kim, MD",{"name":261,"role":92,"phone":25,"phoneExt":25,"email":25},"Ju H Kim, MD",{"facility":263,"status":76,"city":264,"state":265,"zip":266,"country":80,"countryCode":81,"cosmosGeoPoint":267,"geoPoint":271,"contacts":272},"Inova Health System","Falls Church","Virginia","22042",{"type":83,"coordinates":268},[269,270],-77.17109,38.88233,{"lat":270,"lon":269},[273,275],{"name":274,"role":70,"phone":25,"phoneExt":25,"email":25},"Shashank Sinha, MD, MSc",{"name":274,"role":92,"phone":25,"phoneExt":25,"email":25},{"facility":277,"status":76,"city":278,"state":279,"zip":280,"country":80,"countryCode":81,"cosmosGeoPoint":281,"geoPoint":285,"contacts":286},"University of Washington Medical Center","Seattle","Washington","98195-9472",{"type":83,"coordinates":282},[283,284],-122.33207,47.60621,{"lat":284,"lon":283},[287,288],{"name":59,"role":70,"phone":25,"phoneExt":25,"email":25},{"name":59,"role":92,"phone":25,"phoneExt":25,"email":25},{"type":290,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[292,295,297,299],{"name":293,"class":294},"Abbott","INDUSTRY",{"name":296,"class":294},"Boston Scientific Corporation",{"name":298,"class":294},"Abiomed Inc.",{"name":300,"class":6},"Getinge Group","100414889",false,"NCT04682483","Cardiogenic Shock Working Group Registry","CSWG","Inclusion Criteria:\n\n* Patients must have cardiogenic shock.\n\nCardiogenic shock is defined by at least one of the two categories below:\n\n1. At least 2 of the following concurrently at any point during the index hospitalization:\n\n   * Cardiac Index \\\u003C 2.2\n   * PAPI \\\u003C 1.0\n   * Cardiac Power Output ≤ 0.6\n   * MAP \\\u003C 60mmHg or a \\>30mmHg drop in MAP from baseline\n   * SBP \\\u003C 90mmHg or a \\>30mmHg drop in SBP from baseline\n   * Pulse \\> 100\n2. Require at least one acute mechanical circulatory support device, vasopressor or inotrope to maintain values above the above target.\n\nPost-cardiotomy patients must meet the inclusion criteria 72 hours after their surgery to be included in this registry.","ALL","18 Years",{"count":310,"type":311},5000,"ESTIMATED","1 Year","OBSERVATIONAL","The Cardiogenic Shock Working Group is a multicenter registry where we collect de-identified clinical variables from the medical records and follow-up phone calls of shock patients from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes.",[316],"Cardiogenic Shock",[316,318,319,320,321,322,323,324],"mechanical circulatory support","hemodynamics","heart failure","acute myocardial infarction","registry","critical care","clinical outcomes research","2025-06-03",{"date":327,"type":328},"2025-06-06","ACTUAL",{"date":330,"type":328},"2017-12-04",{"date":332,"type":311},"2026-06-01",{"name":5,"class":6},16]