[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617119":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":49,"collaborators":52,"id":56,"slug":10,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":10,"enrollmentInfo":64,"targetDuration":67,"studyType":68,"phases":10,"briefSummary":69,"conditions":70,"keywords":80,"overallStatus":84,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of L'Aquila","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients with ischemic stroke occuring within 28 days after cardiological interventional procedures",null,"Cardiological interventions includes: Percutaneuous Coronary Intervention - PCI, Transcatheter Aortic Valve Replacement - TAVR, Baloon Aortic Valvuloplasy - BAV, Percutaneous Mitral Valve Repair or Replacement, Patent Formaen Ovale - PFO - or Atrial Septal Defects - ASD - Closure, Left Atrial Appendage Closure, Transcatheter Pulmonary Valve Replacement, Percutaneous Closure of Paravalvular Leaks",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Matteo Foschi, MD","CONTACT","+390863499322","matteo.foschi@graduate.univaq.it",[19],{"facility":20,"status":10,"city":21,"state":22,"zip":23,"country":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":31},"Department of Biotechnological and Applied Clinical Sciences","L’Aquila","L'Aquila","67100","Italy",{"type":26,"coordinates":27},"Point",[28,29],13.39954,42.35055,{"lat":29,"lon":28},[32,35,39,42,45,47],{"name":33,"role":15,"phone":16,"phoneExt":10,"email":34},"Simona Sacco, MD","simona.sacco@univaq.it",{"name":36,"role":15,"phone":37,"phoneExt":10,"email":38},"Raffaele Ornello, MD, PhD","+390683499322","raffaele.ornello@univaq.it",{"name":40,"role":41,"phone":10,"phoneExt":10,"email":10},"Lucio D'Anna, MD, PhD","PRINCIPAL_INVESTIGATOR",{"name":43,"role":44,"phone":10,"phoneExt":10,"email":10},"Federico De Santis, MD","SUB_INVESTIGATOR",{"name":46,"role":44,"phone":10,"phoneExt":10,"email":10},"Francesca Gabriele, MD",{"name":48,"role":44,"phone":10,"phoneExt":10,"email":10},"Paola Colantuono, MD",{"type":41,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Simona Sacco","Full Professor of Neurology",[53],{"name":54,"class":55},"Rete delle NeuroCardiologie","UNKNOWN","100617119",false,"NCT07314476","CardioLogical Interventions and Acute strOke Treatment sTudy","CLOT","Inclusion Criteria:\n\n* acute ischemic stroke in adult patient (18 years of age or older) as diagnosed according to the World Health Organization (WHO) criteria;\n* stroke with evidence of CT\u002FMRI DWI\u002FFLAIR acute lesion in the first neuroimaging or in the follow-up at 24-48 h;\n* interventional cardiological procedures performed within 28 days since the stroke onset (Percutaneuous Coronary Intervention - PCI, Transcatheter Aortic Valve Replacement - TAVR, Baloon Aortic Valvuloplasy - BAV, Percutaneous Mitral Valve Repair or Replacement, Patent Formaen Ovale - PFO - or Atrial Septal Defects - ASD - Closure, Left Atrial Appendage Closure, Transcatheter Pulmonary Valve Replacement, Percutaneous Closure of Paravalvular Leaks);\n* written informed consent provided by the patient himself or by proxy (for unconscious patients, cognitively impaired, or aphasic).\n\nExclusion Criteria:\n\n* Stroke-like symptoms due primarily to another non-ischemic\u002Fhemorrhagic acute neurological condition or stroke mimics (e.g. severe hypo- or hyperglycemia, migraine with aura, functional disorders, etc);\n* Spontaneous and post traumatic hemorrhagic stroke or spontaneous\u002Fpost-traumatic subarachnoid hemorrhage or subdural hematoma;\n* AciuImpossibility to achieve written informed consent","ALL","18 Years",{"count":65,"type":66},400,"ESTIMATED","180 Days","OBSERVATIONAL","The study aims to investigate characteristics and prognosis of ischemic stroke cases following cardiological interventions, focusing on the effectiveness and safety of acute ischemic stroke treatments.",[71,72,73,74,75,76,77,78,79],"Acute Ischemic Stroke AIS","Stroke Treatment","PCI Patients","Aortic Valve Replacement","Transcatheter Aortic Valve Replacement (TAVR)","Mitral Valve Repair","Mitral Valve Replacement","Left Atrial Appendage Closure","Transcatheter Pulmonary Valve Replacement (TPVR)",[81,82,83],"acute ischemic stroke","acute ischemic stroke treatments","cardiological intervention","NOT_YET_RECRUITING","2026-01-04",{"date":87,"type":88},"2026-01-07","ACTUAL",{"date":90,"type":66},"2026-01",{"date":92,"type":66},"2028-12",{"name":5,"class":6},1]