About this trial

The aim of the study is to evaluate autonomic function and cerebrovascular control in 60 healthy subjects by means of noninvasive analysis of time series variability.

To this extent, heart period, systolic and mean arterial blood pressure, cerebral blood velocity, peripheral resistances, respiration will be recorded from subjects during an orthostatic challenge.

The interactions between autonomic cardiovascular function, cerebrovascular and peripheral control will be evaluated exploiting the most advanced signal processing techniques.

Eligibility criteria

Qualifiers

age >18

sinus rhythm

informed consent signed

Disqualifiers

age <18

presence of autonomic nervous system diseases or dysfunctions

Trial design

Treatments tested in this trial

  • active standing

Treatment groups

60 Participants
are divided into 1 treatment group

Locations

1
IRCCS Policlinico San Donato20097, San Donato MilaneseMilan, Italy

Sponsors and collaborators

IRCCS Policlinico S. Donato

Lead sponsor