[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588350":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":27,"locations":10,"responsibleParty":33,"collaborators":10,"id":37,"slug":10,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":42,"eligibilityCriteria":43,"healthyVolunteers":38,"sex":44,"minAge":45,"maxAge":46,"enrollmentInfo":47,"targetDuration":10,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":59,"whyStopped":10,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":10},{"fullName":5,"class":6},"Mansoura University","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Control group",null,[12],"Other: control group",{"label":14,"type":15,"description":10,"interventionNames":16},"ultrasound-guided caval-aorta index group","EXPERIMENTAL",[17],"Procedure: ultrasound measurement of caval aorta index",[19,23],{"type":20,"name":21,"description":21,"armGroupLabels":22,"otherNames":10},"PROCEDURE","ultrasound measurement of caval aorta index",[14],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"control group","fixed fluid prescription",[9],[28],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Maha Ahmed Abozeid, Assistant Professor","CONTACT","02-01019216192","mahazed@yahoo.com",{"type":34,"investigatorFullName":35,"investigatorTitle":36,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","maha abou-zeid","Assistant Professor of Anesthesia and Surgical Intensive Care","100588350",false,"NCT06940258","Caval Aorta Index for Fluid Optimization in Traumatic Brain Injury","Efficacy of Caval Aorta Index for Fluid Optimization in Critically Ill Patients With Traumatic Brain Injury","CAI for fluids","Inclusion Criteria:\n\nTraumatic brain injury diagnosed by computed tomography scan Glasgow coma score ≥ 4\n\nExclusion Criteria:\n\nInability to get consent. Pregnant and lactating women Traumatic subarachnoid hemorrhage Spinal cord injury Increased intra-abdominal pressure Abdominal aortic aneurysm Inferior vena cava (IVC) thrombus Portal hypertension Acute corpulmonale Congestive heart failure chronic hemodialysis Surgical intervention other than neurological one within the first 7 days Mechanical ventilation need during first 7 days Cardiac arrest during the first 7 days","ALL","18 Years","60 Years",{"count":48,"type":49},92,"ESTIMATED","INTERVENTIONAL",[52],"NA","Traumatic brain injury is a leading cause of death and disability in trauma patients. As the primary injury cannot be reversed; management strategies must focus on preventing secondary injury by avoiding hypotension and hypoxia besides, maintaining appropriate cerebral perfusion pressure, which is a surrogate for cerebral blood flow.",[55],"Fluid Balance",[57,58],"caval aorta index","traumatic brain injury","NOT_YET_RECRUITING","2025-04-25",{"date":62,"type":63},"2025-04-29","ACTUAL",{"date":65,"type":49},"2025-05-01",{"date":67,"type":49},"2026-07-31",{"name":5,"class":6}]