[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100504078":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":10,"centralContacts":21,"locations":27,"responsibleParty":40,"collaborators":10,"id":42,"slug":10,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":10,"studyType":56,"phases":10,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},{"fullName":5,"class":6},"Centre Hospitalier Henri Laborit","OTHER",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"obsessive compulsive disorder patients",null,[12],"Other: Functional MRI",{"label":14,"type":10,"description":10,"interventionNames":15},"Control Patients",[12],[17],{"type":6,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"Functional MRI","Three cognitive tests will be performed in the MRI, namely a stroop task, an N-back task and a switching task",[14,9],[22],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},"Damien Doolub, MD","CONTACT","+33 (0)5 16 61 18","damien.doolub@ch-poitiers.fr",[28],{"facility":5,"status":29,"city":30,"state":10,"zip":10,"country":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"RECRUITING","Poitiers","France",{"type":33,"coordinates":34},"Point",[35,36],0.34348,46.58261,{"lat":36,"lon":35},[39],{"name":23,"role":24,"phone":10,"phoneExt":10,"email":10},{"type":41,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100504078",false,"NCT05843604","Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder","Cerebral and Cognitive Markers of Treatment Resistance in Obsessive-compulsive Disorder: Towards Personalization of Patient Care","3TOC","Inclusion Criteria:\n\n* Obsessive compulsive disorder diagnosed according to Diagnostic and Statistical Manual 5 criteria (patients will be included regardless of the severity and resistance of their pathology and their levels of executive functions)\n* Understand and accept the constraints of the study\n* Be a beneficiary or affiliated to a Health Insurance scheme\n\nExclusion Criteria:\n\n* Present one of the diagnoses according to the criteria of the DSM 5: schizophrenic disorders, substance abuse or dependence to a substance according to the criteria of the M.I.N.I. version 5.0 (Sheehan et al., 1998)\n* Generalized anxiety disorder, social anxiety, nicotine dependence and history of a major depressive episode are not exclusion criteria according to the M.I.N.I. version 5.0 (Sheehan et al., 1998)\n* Have a serious intercurrent pathology\n* Being a pregnant woman\n* Being a woman of childbearing age without effective contraception.\n* Being hospitalized under duress or on an outpatient basis in a care program\n* Being under judicial protection (reinforced curatorship, guardianship)",true,"ALL","18 Years","70 Years",{"count":54,"type":55},100,"ESTIMATED","OBSERVATIONAL","This study aims to define individual profiles of treatment resistants in order to find indicators and predictors of the therapeutic response.",[59],"OCD",[61],"functional MRI","2026-01-12",{"date":64,"type":65},"2026-01-13","ACTUAL",{"date":67,"type":65},"2023-07-03",{"date":69,"type":55},"2027-09",{"name":5,"class":6},1]