[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590815":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":128,"collaborators":19,"id":131,"slug":19,"hasResults":132,"nctId":133,"briefTitle":134,"officialTitle":134,"acronym":135,"eligibilityCriteria":136,"healthyVolunteers":132,"sex":137,"minAge":138,"maxAge":19,"enrollmentInfo":139,"targetDuration":19,"studyType":142,"phases":143,"briefSummary":145,"conditions":146,"keywords":148,"overallStatus":151,"whyStopped":19,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":156,"completionDateStruct":158,"leadSponsor":160,"locationsCount":161},{"fullName":5,"class":6},"Central Hospital, Nancy, France","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cerebral Near infrared spectroscopy (NIRSc) group","EXPERIMENTAL","The use of cerebral Near infrared spectroscopy to predict the neurological prognosis of patients treated for out-of-hospital cardiac arrest.",[13],"Other: Cerebral Near infrared spectroscopy (NIRSc).",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Cerebral Near infrared spectroscopy (NIRSc).","Continuous cerebral near-infrared spectroscopy (NIRSc) during resuscitation in a patient treated for out-of-hospital cardiac arrest (OHCA).",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Nicolas GIRERD, MD-PhD","CHRU de NANCY","STUDY_CHAIR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":19,"email":30},"Deborah JAEGER, MD","CONTACT","+33 (0) 3 83 85 85 85","D.JAEGER@chru-nancy.fr",{"name":32,"role":28,"phone":29,"phoneExt":19,"email":33},"Tahar CHOUIHED, MD PHD","T.CHOUIHEDMAHJOUB@chru-nancy.fr",[35,53,68,81,97,113],{"facility":36,"status":19,"city":37,"state":19,"zip":38,"country":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"CH Colmar- Urgences - SAMU-SMUR","Colmar","68000","France",{"type":41,"coordinates":42},"Point",[43,44],7.35584,48.08078,{"lat":44,"lon":43},[47,51],{"name":48,"role":28,"phone":49,"phoneExt":19,"email":50},"Yannick GOTTWALLES, MD","+33 (0) 3 89 12 40 00","yannick.gottwalles@ch-colmar.fr",{"name":48,"role":52,"phone":19,"phoneExt":19,"email":19},"PRINCIPAL_INVESTIGATOR",{"facility":54,"status":19,"city":55,"state":19,"zip":56,"country":39,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"CHR Metz-Thionville - Mercy hospital -Urgences - SAMU-SMUR","Metz","5700",{"type":41,"coordinates":58},[59,60],6.17269,49.11911,{"lat":60,"lon":59},[63,67],{"name":64,"role":28,"phone":65,"phoneExt":19,"email":66},"Philippe Alarcon, MD","+33 (0) 3 87 55 31 31","philippe.alarcon@chr-metz-thionville.fr",{"name":64,"role":52,"phone":19,"phoneExt":19,"email":19},{"facility":69,"status":19,"city":70,"state":19,"zip":71,"country":39,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"CHRU NANCY - urgences SAMUR SMUR- Central hospital","Nancy","54000",{"type":41,"coordinates":73},[74,75],6.18496,48.68439,{"lat":75,"lon":74},[78,80],{"name":27,"role":28,"phone":79,"phoneExt":19,"email":30},"+33 (0)3 83 85 85 85",{"name":27,"role":52,"phone":19,"phoneExt":19,"email":19},{"facility":82,"status":19,"city":83,"state":19,"zip":84,"country":39,"cosmosGeoPoint":85,"geoPoint":89,"contacts":90},"CHU Reims - ugences - SAMU-SMUR","Reims","51100",{"type":41,"coordinates":86},[87,88],4.02853,49.26526,{"lat":88,"lon":87},[91,95],{"name":92,"role":28,"phone":93,"phoneExt":19,"email":94},"Stéphane GENNAI, MD","+33 (0)3 26 78 78 78","sgennai@chu-reims.fr",{"name":96,"role":52,"phone":19,"phoneExt":19,"email":19},"Séphane GENNAI, MD",{"facility":98,"status":19,"city":99,"state":19,"zip":100,"country":39,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"Hôpitaux universitaire de Strasbourg - Urgences - SAMU-SMUR","Strasbourg","67200",{"type":41,"coordinates":102},[103,104],7.74553,48.58392,{"lat":104,"lon":103},[107,111],{"name":108,"role":28,"phone":109,"phoneExt":19,"email":110},"Anne Weiss, MD","+33 (0)3 88 11 67 68","anne.weiss@chru-strasbourg.fr",{"name":112,"role":52,"phone":19,"phoneExt":19,"email":19},"Anne WEISS, MD",{"facility":114,"status":19,"city":115,"state":19,"zip":116,"country":39,"cosmosGeoPoint":117,"geoPoint":121,"contacts":122},"CHR Troyes- Urgences - SAMU-SMUR","Troyes","10000",{"type":41,"coordinates":118},[119,120],4.08524,48.30073,{"lat":120,"lon":119},[123,127],{"name":124,"role":28,"phone":125,"phoneExt":19,"email":126},"Alain HUGEROT, MD","+33 (3) 25 49 49 49","alain.hugerot@ch-troyes.fr",{"name":124,"role":52,"phone":19,"phoneExt":19,"email":19},{"type":52,"investigatorFullName":129,"investigatorTitle":130,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"JAEGER Deborah","Coordinating Investigator","100590815",false,"NCT06972329","Cerebral Near Infrared Spectroscopy in Out-of-Hospital Cardiac Arrest and Neurological Prognosis","NISOHCA","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Non-traumatic out-of-hospital cardiac arrest witnessed and managed by the mobile emergency unit (SMUR).\n\nExclusion Criteria:\n\n* Scalp\u002Fcranial or facial injury preventing the placement of electrodes for NIRS measurement.\n* Spontaneous cardiac activity upon the arrival of the SMUR.\n* Decision by the SMUR physician not to initiate specialized resuscitation.","ALL","18 Years",{"count":140,"type":141},542,"ESTIMATED","INTERVENTIONAL",[144],"NA","Out-of-hospital cardiac arrest (OHCA) prognosis remains poor : 7% of patients surviving without neurological impairment.\n\n65% of patients dying after hospital admission were neurologically impaired. When treating a patient with CA, neurological outcome remains extremely difficult to predict, especially in the pre-hospital setting. Practitioners have very little objective information to help them with neuropronostication.\n\nAlthough an EtCO2 level of \\\u003C 10 mmHg is associated with a poor neurological prognosis, European recommendations point out that this data alone is not currently sufficient to predict a patient's prognosis or to make a decision to stop resuscitation. Current recommendations do not suggest any other objective parameter during resuscitation for neuropronostication of patients with out-of-hospital cardiac arrest.\n\nCerebral tissue oxygen saturation (rSO2) is measured using the near infrared spectrometry (NIRS) technique. Cerebral NIRS (cNIRS) enables non-invasive measurement of changes in cerebral oximetry during the management of a cardiac arrest (CA).\n\nVarious clinical studies conducted over the last ten years have demonstrated that there is a probable link between cNIRS levels during resuscitation and return of spontaneous circulation (ROSC), but a clear threshold value has not been defined.\n\nThe aim of the NISOHCA study is to confirm that a 40% threshold of cNIRS in the pre-hospital setting for OHCA can specifically predict survival with good neurological outcome at D90 .",[147],"Out-of-hospital Cardiac Arrest (OHCA)",[149,150],"Out-of-hospital cardiac arrest","Cerebral Near infrared spectroscopy (NIRSc)","NOT_YET_RECRUITING","2025-05-12",{"date":154,"type":155},"2025-05-15","ACTUAL",{"date":157,"type":141},"2025-11",{"date":159,"type":141},"2028-02",{"name":5,"class":6},6]