[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100548809":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":44,"collaborators":10,"id":47,"slug":10,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":10,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":10,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},{"fullName":5,"class":6},"Universitair Ziekenhuis Brussel","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Left atrial mapping group in patients without atrial fibrillation",null,"Inclusion criteria:\n\n* Age ≥ 18 years old.\n* Absence of a prior history of atrial fibrillation or flutter.\n* Patients presenting for ablation of any ventricular tachycardia related to structural heart disease or any ventricular arrhythmia with a CHA2DS2-VASc score ≥ 2.\n\nExclusion criteria:\n\n* Presence of thrombus in the left atrial appendage.\n* Complications related to the index procedure.\n* Insufficient quality of the left atrial electroanatomical map.",[13],"Diagnostic Test: Left atrial electroanatomical mapping",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Left atrial electroanatomical mapping","Left atrial electroanatomical mapping (substrate and functional mapping)",[9],[21],{"name":22,"affiliation":5,"role":23},"Andrea Sarkozy, MD, PhD","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","0032 02476 3657","Andrea.Sarkozy@uzbrussel.be",[30],{"facility":5,"status":31,"city":32,"state":33,"zip":34,"country":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","Jette","Brussels Capital","1090","Belgium",{"type":37,"coordinates":38},"Point",[39,40],4.33419,50.87309,{"lat":40,"lon":39},[43],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},{"type":23,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Andrea Sarkozy","Clinical Professor","100548809",false,"NCT06425822","Characterization of Left Atrial Substrate in Patients With Ventricular Arrhythmias","CLASS-VA","Inclusion Criteria:\n\n* Absence of a prior history of atrial fibrillation or flutter.\n* Patients presenting for ablation of any ventricular tachycardia related to structural heart disease or any ventricular arrhythmia with a CHA2DS2-VASc score ≥ 2.\n\nExclusion criteria:\n\n* Presence of thrombus in the left atrial appendage.\n* Complications related to the index procedure.\n* Insufficient quality of the left atrial electroanatomical map.","ALL","18 Years",{"count":56,"type":57},50,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to analyze the characteristics of left atrial electroanatomical maps in patients without a history of atrial fibrillation but with a high clinical risk of developing it, as indicated by the presence of structural heart disease or a CHA2DS2-VASc score ≥ 2 points. The study cohort will be compared to a historical cohort of patients with diagnosed atrial fibrillation in a propensity-matched fashion.\n\nThe main questions it aims to answer are:\n\n* Are the left atrial electroanatomical changes a consequence or a precursor to the development of atrial fibrillation?\n* Are the left atrial electroanatomical findings different between patients with atrial fibrillation and those at high risk of developing it?\n* What is the prognostic impact of left atrial pathologic changes in patients without diagnosed atrial fibrillation in terms of cardiovascular outcomes?",[61],"Atrial Remodeling","2024-05-21",{"date":64,"type":65},"2024-05-22","ACTUAL",{"date":67,"type":65},"2023-11-08",{"date":69,"type":57},"2027-10-31",{"name":5,"class":6},1]