[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100593052":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":146,"collaborators":18,"id":149,"slug":18,"hasResults":150,"nctId":151,"briefTitle":152,"officialTitle":152,"acronym":153,"eligibilityCriteria":154,"healthyVolunteers":150,"sex":155,"minAge":156,"maxAge":18,"enrollmentInfo":157,"targetDuration":18,"studyType":160,"phases":161,"briefSummary":163,"conditions":164,"keywords":18,"overallStatus":41,"whyStopped":18,"lastUpdateSubmitDate":168,"lastUpdatePostDateStruct":169,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":177},{"fullName":5,"class":6},"Helsinki University Central Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cholecystectomy","ACTIVE_COMPARATOR","Laparoscopic cholecystectomy is done within 2 weeks after endoscopic removal of common bile duct stones.",[13],"Procedure: Laparoscopic cholecystectomy",{"label":15,"type":16,"description":17,"interventionNames":18},"Wait-and-see","NO_INTERVENTION","After endoscopic removal of common bile duct stones, patients are managed non-operatively. During the follow-up cholecystectomy will be available on demand.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"PROCEDURE","Laparoscopic cholecystectomy","Laparoscopic cholecystectomy within 2 weeks after endoscopic removal of common bile duct stone",[9],[26],{"name":27,"affiliation":5,"role":28},"Panu Mentula, MD, PhD","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":33},"CONTACT","+358504270183","panu.mentula@hus.fi",{"name":35,"role":31,"phone":36,"phoneExt":18,"email":37},"Päivi Siironen, MD, PhD","+358504271343","paivi.siironen@hus.fi",[39,55,64,74,82,90,98,106,114,122,130,138],{"facility":40,"status":41,"city":42,"state":18,"zip":18,"country":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Helsinki University Hospital, Jorvi","RECRUITING","Espoo","Finland",{"type":45,"coordinates":46},"Point",[47,48],24.6522,60.2052,{"lat":48,"lon":47},[51],{"name":52,"role":31,"phone":53,"phoneExt":18,"email":54},"Hanna Malmi, MD, PhD","+358505123553","hanna.malmi@hus.fi",{"facility":56,"status":57,"city":58,"state":18,"zip":18,"country":43,"cosmosGeoPoint":59,"geoPoint":63,"contacts":18},"Kanta-Häme Central Hospital","NOT_YET_RECRUITING","Hämeenlinna",{"type":45,"coordinates":60},[61,62],24.46434,60.99596,{"lat":62,"lon":61},{"facility":65,"status":41,"city":66,"state":18,"zip":18,"country":43,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"Helsinki University Hospital, Meilahti","Helsinki",{"type":45,"coordinates":68},[69,70],24.93545,60.16952,{"lat":70,"lon":69},[73],{"name":35,"role":31,"phone":36,"phoneExt":18,"email":37},{"facility":75,"status":57,"city":76,"state":18,"zip":18,"country":43,"cosmosGeoPoint":77,"geoPoint":81,"contacts":18},"Pohjois-Karjala Central Hospital","Joensuu",{"type":45,"coordinates":78},[79,80],29.76316,62.60118,{"lat":80,"lon":79},{"facility":83,"status":57,"city":84,"state":18,"zip":18,"country":43,"cosmosGeoPoint":85,"geoPoint":89,"contacts":18},"Keski-Suomi Central Hospital","Jyväskylä",{"type":45,"coordinates":86},[87,88],25.72088,62.24147,{"lat":88,"lon":87},{"facility":91,"status":57,"city":92,"state":18,"zip":18,"country":43,"cosmosGeoPoint":93,"geoPoint":97,"contacts":18},"Kymenlaakso Central Hospital","Kotka",{"type":45,"coordinates":94},[95,96],26.94582,60.4664,{"lat":96,"lon":95},{"facility":99,"status":57,"city":100,"state":18,"zip":18,"country":43,"cosmosGeoPoint":101,"geoPoint":105,"contacts":18},"Kuopio University Hospital","Kuopio",{"type":45,"coordinates":102},[103,104],27.67703,62.89238,{"lat":104,"lon":103},{"facility":107,"status":57,"city":108,"state":18,"zip":18,"country":43,"cosmosGeoPoint":109,"geoPoint":113,"contacts":18},"Päijät-Häme Central Hospital","Lahti",{"type":45,"coordinates":110},[111,112],25.66151,60.98267,{"lat":112,"lon":111},{"facility":115,"status":57,"city":116,"state":18,"zip":18,"country":43,"cosmosGeoPoint":117,"geoPoint":121,"contacts":18},"Oulu University Hospital","Oulu",{"type":45,"coordinates":118},[119,120],25.46816,65.01236,{"lat":120,"lon":119},{"facility":123,"status":57,"city":124,"state":18,"zip":18,"country":43,"cosmosGeoPoint":125,"geoPoint":129,"contacts":18},"Tampere University Hospital","Tampere",{"type":45,"coordinates":126},[127,128],23.78712,61.49911,{"lat":128,"lon":127},{"facility":131,"status":57,"city":132,"state":18,"zip":18,"country":43,"cosmosGeoPoint":133,"geoPoint":137,"contacts":18},"Turku University Hospital","Turku",{"type":45,"coordinates":134},[135,136],22.26869,60.45148,{"lat":136,"lon":135},{"facility":139,"status":57,"city":140,"state":18,"zip":18,"country":43,"cosmosGeoPoint":141,"geoPoint":145,"contacts":18},"Vaasa Central Hospital","Vaasa",{"type":45,"coordinates":142},[143,144],21.61577,63.096,{"lat":144,"lon":143},{"type":28,"investigatorFullName":147,"investigatorTitle":148,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Panu Mentula","MD, PhD, Head of Emergency Surgery","100593052",false,"NCT07001423","ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in Elderly","COFFEE","Inclusion Criteria:\n\n* Common bile duct stones cleared after Endoscopic Retrograde Cholangio Pancreatography (ERCP)\n* Age \\>= 80 years or age 75-79 years with a Charlson Comorbidity index \\>=2\n* gallbladder in situ\n\nExclusion Criteria:\n\n* Acute Cholecystitis\n* Biliary Pancreatitis\n* Severe or moderately severe post-ERCP pancreatitis\n* Chronic pancreatitis\n* Bile duct pathology\n* Widespread malignancy\n* Unable to give consent","ALL","75 Years",{"count":158,"type":159},400,"ESTIMATED","INTERVENTIONAL",[162],"NA","The goal of this study is to compare safety and efficacy of laparoscopic cholecystectomy versus wait-and-see policy after endoscopic removal of common bile duct stones in elderly. The primary endpoint is a composite outcome: Death or major postoperative complications or recurrent biliary disease within 1 year after randomization.",[165,166,167],"Cholecystectomy, Laparoscopic","Choledocholithiasis","Cholelithiasis","2025-10-02",{"date":170,"type":171},"2025-10-07","ACTUAL",{"date":173,"type":159},"2025-10-03",{"date":175,"type":159},"2032-08-31",{"name":5,"class":6},12]