[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100375990":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":31,"locations":40,"responsibleParty":57,"collaborators":10,"id":59,"slug":10,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":10,"enrollmentInfo":69,"targetDuration":72,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Nanjing First Hospital, Nanjing Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"AIS group",null,"This group includes patients with acute ischemic stroke (AIS).",[13],"Genetic: Sequencing of circRNA\u002FmiRNA\u002FlncRNA",{"label":15,"type":10,"description":16,"interventionNames":17},"HC group","This group includes healthy controls (HC).",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"GENETIC","Sequencing of circRNA\u002FmiRNA\u002FlncRNA","Next generation sequencing of circular RNA (circRNA), micro-RNA (miRNA) and long non-coding RNA (lncRNA)",[9,15],[25],"Quantitative Real-time polymerase chain reaction",[27],{"name":28,"affiliation":29,"role":30},"Junshan Zhou, Professor","Nanjing Medical University","STUDY_CHAIR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":10,"email":36},"Junshan Zhou, M.D.","CONTACT","+8602587726218","zhjsh333@126.com",{"name":38,"role":34,"phone":35,"phoneExt":10,"email":39},"Qiwen Deng, M.D.","qiw_deng@163.com",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Nanjing","Jiangsu","210006","China",{"type":48,"coordinates":49},"Point",[50,51],118.77778,32.06167,{"lat":51,"lon":50},[54,56],{"name":33,"role":34,"phone":55,"phoneExt":10,"email":36},"+86025-87726218",{"name":38,"role":34,"phone":55,"phoneExt":10,"email":39},{"type":58,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100375990",false,"NCT04175691","Circulating Non-coding RNA in Acute Ischemic Stroke (AISRNA)","Clinical Significance of Circulating Non-coding RNA in Acute Ischemic Stroke (AISRNA)","AISRNA","Inclusion Criteria:\n\n* Aged 18 years or older\n* Confirmed acute ischemic stroke by a diffusion-weighted imaging-position lesion on magnetic resonance imaging (MRI) and a new lesion on a brain computed tomography (CT) scan\n* Within 72 hours of symptom onset\n* Good performance status\n* Signed an approved informed consents\n\nExclusion Criteria:\n\n-a history of hemorrhagic infarction, chronic kidney\u002Fliver diseases, peripheral arterial occlusive disease, active malignant disease, and inflammatory or infectious diseases",true,"ALL","18 Years",{"count":70,"type":71},500,"ESTIMATED","90 Days","OBSERVATIONAL","AISRNA is to analyze the expression pattern of circular RNA (circRNA), micro-RNA (miRNA) and long non-coding RNA (lncRNA) by next-generation sequencing in patients with acute ischemic stroke and healthy control. The candidate circRNA\u002FmiRNA\u002FlncRNA will be verified as biomarkers for the detection and prognosis of acute ischemic stroke.",[76,77],"Acute Stroke","Ischemic Stroke",[79,80,81,82],"acute ischemic stroke","noncoding RNA","clinical significance","outcome","2026-04-10",{"date":85,"type":86},"2026-04-15","ACTUAL",{"date":88,"type":86},"2019-11-24",{"date":90,"type":71},"2026-12-31",{"name":5,"class":6},1]