[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100535758":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":22,"centralContacts":26,"locations":35,"responsibleParty":97,"collaborators":99,"id":106,"slug":10,"hasResults":107,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":10,"eligibilityCriteria":111,"healthyVolunteers":107,"sex":112,"minAge":113,"maxAge":114,"enrollmentInfo":115,"targetDuration":10,"studyType":118,"phases":10,"briefSummary":119,"conditions":120,"keywords":10,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":131},{"fullName":5,"class":6},"University Children's Hospital, Zurich","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"NovoSorb® BTM and STSG",null,"Full thickness skin defect qualifying for coverage with the dermal substitute NovoSorb® BTM before transplantation with a split-thickness skin graft (STSG) according to clinical routine",[13],"Other: Standard of care",{"label":15,"type":10,"description":16,"interventionNames":17},"STSG alone","Full thickness skin defect qualifying for coverage with split-thickness skin graft (STSG) alone according to clinical routine",[13],[19],{"type":6,"name":20,"description":20,"armGroupLabels":21,"otherNames":10},"Standard of care",[9,15],[23],{"name":24,"affiliation":5,"role":25},"Sophie Böttcher, MD","PRINCIPAL_INVESTIGATOR",[27,31],{"name":24,"role":28,"phone":29,"phoneExt":10,"email":30},"CONTACT","+41442497228","sophie.boettcher@kispi.uzh.ch",{"name":32,"role":28,"phone":33,"phoneExt":10,"email":34},"Vivienne Woodtli, dipl. med.","+41442497586","vivenne.woodtli@kispi.uzh.ch",[36,54,71,83],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Cantonal Hospital Aarau","RECRUITING","Aarau","Canton of Aargau","5001","Switzerland",{"type":44,"coordinates":45},"Point",[46,47],8.04422,47.39254,{"lat":47,"lon":46},[50],{"name":51,"role":28,"phone":52,"phoneExt":10,"email":53},"jan Plock, Prof. Dr. med.","0041628384731","plastischechirurgie@ksa.ch",{"facility":55,"status":38,"city":56,"state":57,"zip":58,"country":42,"cosmosGeoPoint":59,"geoPoint":63,"contacts":64},"University Children's Hospital Zurich","Zurich","Canton of Zurich","8032",{"type":44,"coordinates":60},[61,62],8.55,47.36667,{"lat":62,"lon":61},[65,66,70],{"name":24,"role":28,"phone":29,"phoneExt":10,"email":30},{"name":67,"role":28,"phone":68,"phoneExt":10,"email":69},"Vivienne Woodtli","+41442667078","vivienne.woodtli@kispi.uzh.ch",{"name":24,"role":25,"phone":10,"phoneExt":10,"email":10},{"facility":72,"status":38,"city":56,"state":57,"zip":73,"country":42,"cosmosGeoPoint":74,"geoPoint":76,"contacts":77},"University Hospital Zurich","8090",{"type":44,"coordinates":75},[61,62],{"lat":62,"lon":61},[78,82],{"name":79,"role":28,"phone":80,"phoneExt":10,"email":81},"Bong-Sung Kim, Prof.","+41432538932","bong-sung.kim@usz.ch",{"name":79,"role":25,"phone":10,"phoneExt":10,"email":10},{"facility":84,"status":38,"city":85,"state":85,"zip":86,"country":42,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"Cantonal Hospital Winterthur","Winterthur","8400",{"type":44,"coordinates":88},[89,90],8.72413,47.50564,{"lat":90,"lon":89},[93],{"name":94,"role":28,"phone":95,"phoneExt":10,"email":96},"Abdul R Jandali, Dr. med.","0041522662420","abdulrahman.jandali@ksw.ch",{"type":98,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[100,102,104],{"name":101,"class":6},"University of Zurich",{"name":103,"class":6},"Kantonsspital Aarau",{"name":105,"class":6},"Kantonsspital Winterthur KSW","100535758",false,"NCT06255990","Clinical and Histological Study of a Novel Dermal Substitute","Clinical and Histological Study of a Novel Dermal Substitute, NovoSorb® BTM, Used in the Treatment of Full-thickness Skin Defects","Inclusion Criteria:\n\n* Age: 1 to 75 years\n* Full-thickness skin defect qualifying for coverage with the dermal substitute NovoSorb® BTM before transplantation with a STSG:\n\n  * Acute cases: burn injury, soft tissue injury, skin necrosis after purpura fulminans or similar condition\n  * Reconstructive cases (elective surgery): e.g. scar formation after burn injury, giant congenital nevus, defect after removal of skin tumor, skin defect due to other surgical procedures\n* Documented medical treatment decision of covering the full-thickness skin defects with either the two-step BTM\u002FSTSG procedure or with STSG alone or by using both techniques on different wound areas\n* Informed consent by patients\u002Fparents or other legal representative\n\nExclusion Criteria:\n\n* Infected wounds needing surgical procedure other than a dermal template\n* Patients with known underlying or concomitant medical conditions that may interfere with normal wound healing (e.g. immune deficiency, systemic skin disease, any kind of congenital defect of metabolism including diabetes)\n* Previous enrolment of the patient into the current study\n* Adolescent\u002FAdult patients or in case of children their parents\u002Flegal representatives unable to comply with the study protocol\n* Pregnant or breast feeding females","ALL","1 Year","75 Years",{"count":116,"type":117},42,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to compare a novel dermal substitute to a the current standard procedure in the treatment of full thickness skin defects.\n\nThe main questions aim to answer are:\n\n• Is the skin elasticity treated with the novel dermal substitute better than the skin elasticity treated with the current standard procedure Participants skin elasticity will be measured by Cutometer® MPA-580 assessment.",[121],"Skin Transplantation","2026-03-30",{"date":124,"type":125},"2026-04-03","ACTUAL",{"date":127,"type":125},"2024-01-15",{"date":129,"type":117},"2027-06",{"name":5,"class":6},4]