The goal of this clinical trial is to compare the clinical effects of using Ringer's Lactate and Sterofundin/ Plasmalyte as maintenance fluids in adult patients who have undergone abdominal surgery and are septic.
The primary outcome will be the change in serum lactate levels. Secondary outcomes will include renal function parameters, qSOFA scores, and the incidence of postoperative complications within the first 72 hours following surgery.
Underwent Abdominal Surgery and postoperative length of stay is more than 24 hours
ASA 1 to 4
Diagnosis of sepsis (qSOFA score 2 or more)
Patients with Renal failure/hepatic failure/severe metabolic acidosis
Patients requiring renal replacement therapy prior to enrolment
Patients with suspected poisoning
Pregnant women
Parallel
Ringer's Lactate Crystalloid Solutions
Other interventionA balanced crystalloid solution containing sodium, potassium, calcium, chloride, and lactate as a buffer. Used at a standard maintenance rate for adult postoperative patients.
Sterofundin (Bolus of crystalloids)
Other interventionA balanced, multi-electrolyte crystalloid solution containing acetate and malate as buffers instead of lactate. Designed to more closely match plasma electrolyte composition, with a lower chloride concentration than RL.
serum lactate
Measurement: Serum lactate levels will be measured from blood samples. Method: Standard laboratory assays will be used to quantify lactate concentration. Purpose: To assess the effect of maintenance fluids (Ringer's Lactate vs. Sterofundin) on lactate clearance and tissue perfusion in septic adult patients following abdominal surgery. Units: mmol/L
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