[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100564915":3},{"organization":4,"outcomesModule":7,"designInfo":17,"detailedDescription":16,"studyPopulation":16,"armGroups":26,"interventions":37,"overallOfficials":16,"centralContacts":45,"locations":16,"responsibleParty":51,"collaborators":16,"id":56,"slug":16,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":16,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":16,"enrollmentInfo":64,"targetDuration":16,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":16,"overallStatus":73,"whyStopped":16,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":16},{"fullName":5,"class":6},"Manipal University College Malaysia","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":16},[9,13],{"measure":10,"description":11,"timeFrame":12},"Fracture of material","Different fracture patterns and retention failures may occur in relation to the type of restoration: cracks, chipping\u002F delamination, bulk fractures, or incomplete and complete loss of retention. Assessed by Visual examination and short air drying. Criteria set from Clinically excellent\u002Fvery good(sufficient) (Score 1) to Clinically poor (entirely insufficient)(Score 5)","From treatment to 3-6 months follow up",{"measure":14,"description":15,"timeFrame":12},"Marginal adaptation","There are different interfaces between the dental hard tissue, restorative material, and adhesive and\u002For luting resin\u002Fcement layer. Each interface can degrade and potentially alter marginal adaptation. In clinical practice, it is impossible to distinguish failures between the different interfaces. Therefore, only the marginal adaptation as such can be assessed by visual examination and short air drying.\n\nScores given depending upon the quality of restoration from Clinically excellent\u002Fvery good (sufficient) (Score 1) to Clinically poor (entirely insufficient) (Score 5)",null,{"allocation":18,"interventionModel":19,"interventionModelDescription":16,"primaryPurpose":20,"observationalModel":16,"timePerspective":16,"maskingInfo":21},"RANDOMIZED","FACTORIAL","TREATMENT",{"masking":22,"maskingDescription":16,"whoMasked":23},"DOUBLE",[24,25],"PARTICIPANT","INVESTIGATOR",[27,32],{"label":28,"type":29,"description":16,"interventionNames":30},"Universal single bond adhesive","ACTIVE_COMPARATOR",[31],"Other: Universal single bond adhesive",{"label":33,"type":34,"description":16,"interventionNames":35},"DMSO application before Universal single bond adhesive","EXPERIMENTAL",[31,36],"Other: DMSO",[38,41],{"type":6,"name":28,"description":39,"armGroupLabels":40,"otherNames":16},"Will be applied and light cured for 20 seconds.",[33,28],{"type":6,"name":42,"description":43,"armGroupLabels":44,"otherNames":16},"DMSO","DMSO application on tooth followed by active application of universal single bond adhesive and light cured for 20 seconds.",[33],[46],{"name":47,"role":48,"phone":49,"phoneExt":16,"email":50},"Anchu Rachel Thomas","CONTACT","1-700-811-662","rachel.thomas@manipal.edu.my",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":55,"oldNameTitle":16,"oldOrganization":16},"PRINCIPAL_INVESTIGATOR","Philip Pradeep","Associate Professor","Melaka Manipal Medical College","100564915",false,"NCT06635382","Clinical Evaluation of Dimethyl Sulfoxide Wet Bonding Technique","Clinical Evaluation of Dimethyl Sulfoxide Wet Bonding Technique: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Two similar non carious cervical lesions (NCCLs) on the facial\u002Flabial surfaces of premolars.\n* NCCLs of score 1-3 on the Smith and Knight tooth wear index.\n* Favorable occlusion and teeth are in normal contact.\n\nExclusion Criteria:\n\n* NCCLs on the lingual surface.\n* Medically compromised individuals.\n* Periodontally compromised teeth.\n* Bruxism and visible wear facets in the posterior dentition.\n* Fractured or visibly cracked premolars and canines.\n* Known allergies to resin-based restorative materials.\n* Presently undergoing orthodontic treatment.\n* Abutment teeth for fixed or removable prostheses.","ALL","18 Years",{"count":65,"type":66},68,"ESTIMATED","INTERVENTIONAL",[69],"NA","Dimethyl sulfoxide (DMSO) wet bonding has shown promising results in several in vitro studies. However, there are a lack of clinical trials which prove the advantages of this technique. The aim of the study is to clinically assess the effect of DMSO wet bonding on composite restoration in non carious cervical lesions.",[72],"Dimethyl Sulfoxide","NOT_YET_RECRUITING","2024-10-08",{"date":76,"type":77},"2024-10-10","ACTUAL",{"date":79,"type":66},"2024-10-20",{"date":81,"type":66},"2025-04-01",{"name":5,"class":6}]