[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558941":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":21,"studyPopulation":22,"armGroups":23,"interventions":11,"overallOfficials":11,"centralContacts":30,"locations":35,"responsibleParty":53,"collaborators":11,"id":57,"slug":11,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":11,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":11,"enrollmentInfo":65,"targetDuration":11,"studyType":68,"phases":11,"briefSummary":69,"conditions":70,"keywords":71,"overallStatus":49,"whyStopped":11,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Taichung Veterans General Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"Overall survival",null,"From the initial treatment until April 2024",[14,16],{"measure":15,"description":11,"timeFrame":12},"Progress free survival",{"measure":17,"description":11,"timeFrame":12},"Tumor response",{"allocation":11,"interventionModel":11,"interventionModelDescription":11,"primaryPurpose":11,"observationalModel":19,"timePerspective":20,"maskingInfo":11},"COHORT","RETROSPECTIVE","Colorectal cancer (CRC) is the third most common cancer worldwide. The clinical outcomes from CRC treatments are often unsatisfactory for the majority of patients. The tumor microenvironment (TME) plays an important role to regulate tumor growth, progression, and metastasis and can limit the efficacy of cancer therapies. Therefore, targeting TME could provide an efficient approach for cancer treatment.\n\nAstragalus Polysaccharide Injection, an immunomodulator, which can stimulate medullary hematopoiesis and enhance immune function. It also can modulate TME. Astragalus Polysaccharide Injection has been approved as a prescription drug for alleviating cancer-related fatigue by the Taiwan Food and Drug Administration (TFDA).\n\nIn this retrospective study, we will collect clinical data and survival status of colorectal cancer patients undergoing anti-cancer treatment from their medical records with and without immunomodulator, Astragalus polysaccharide Injection. It can be used to understand the possible clinical benefit of immunomodulator plus anti-cancer therapies for patients with colorectal cancer, and physicians can refer to these results to give patients the suitable treatment recommendations.","Colorectal Cancer",[24,27],{"label":25,"type":11,"description":26,"interventionNames":11},"Cancer treatment with immunomodulator","CRC patients had previously received cancer therapies along with immunomodulator",{"label":28,"type":11,"description":29,"interventionNames":11},"Cancer treatment without immunomodulator","CRC patients had previously received cancer therapies without immunomodulator",[31],{"name":32,"role":33,"phone":11,"phoneExt":11,"email":34},"Chou-Chen Chen, M.D.","CONTACT","ccchen24615237@gmail.com",[36,48],{"facility":37,"status":38,"city":39,"state":11,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":11},"Chung-Shan Medical University Hospital","NOT_YET_RECRUITING","Taichung","Taiwan","TW",{"type":43,"coordinates":44},"Point",[45,46],120.6839,24.1469,{"lat":46,"lon":45},{"facility":5,"status":49,"city":39,"state":11,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":50,"geoPoint":52,"contacts":11},"RECRUITING",{"type":43,"coordinates":51},[45,46],{"lat":46,"lon":45},{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Chou-Chen Chen","Attending Physician","100558941",false,"NCT06557668","Clinical Outcomes of Treatment With Immunomodulator Plus Cancer Therapies for Patients With Colorectal Cancer","Clinical Outcomes of Treatment With Immunomodulator Plus Standard Anti-cancer Therapies for Patients With Colorectal Cancer: A Retrospective Study","Inclusion Criteria:\n\n* Aged 20 years and older.\n* Patients who have been given a diagnosis of colorectal cancer.\n* Patients had previously initiated anti-cancer therapies between January 1, 2020, and Apr 30, 2024.\n\nExclusion Criteria:\n\n* None","ALL","20 Years",{"count":66,"type":67},250,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate the survival and treatment outcomes among colorectal cancer patients undergoing anti-cancer treatment, both with and without an immunomodulator.",[22],[22,72,73],"Astragalus Polysaccharides","Survival","2026-01-27",{"date":76,"type":77},"2026-01-29","ACTUAL",{"date":79,"type":77},"2024-08-20",{"date":81,"type":67},"2026-07",{"name":5,"class":6},2]