[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100561892":3},{"organization":4,"outcomesModule":7,"designInfo":52,"detailedDescription":36,"studyPopulation":55,"armGroups":56,"interventions":64,"overallOfficials":36,"centralContacts":69,"locations":36,"responsibleParty":75,"collaborators":36,"id":79,"slug":36,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":36,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":36,"studyType":91,"phases":36,"briefSummary":92,"conditions":93,"keywords":36,"overallStatus":95,"whyStopped":36,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":36},{"fullName":5,"class":6},"The Second Affiliated Hospital of Kunming Medical University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":36},[9],{"measure":10,"description":11,"timeFrame":12},"operating time","Record the patient\\'s surgical time","During surgery",[14,18,21,24,27,31,34,37,39,41,44,48],{"measure":15,"description":16,"timeFrame":17},"nutritional status","Patients were assessed for risk of malnutrition by the Nutritional Risk Screening Scale (NRS-2002). A score of ≥3 indicated that the patient was at risk of malnutrition.","Preoperative",{"measure":19,"description":20,"timeFrame":17},"bowel habit","The patient was asked whether there were increased frequency of stool, changes in stool characteristics, constipation and other conditions before surgery",{"measure":22,"description":23,"timeFrame":12},"Surgical Procedures","Record whether the patient underwent laparoscopic surgery or open surgery",{"measure":25,"description":26,"timeFrame":12},"hemorrhage","Record the patient\\'s intraoperative bleeding volume",{"measure":28,"description":29,"timeFrame":30},"Albumin","Record the patient\\'s albumin levels before and 24 hours after surgery","Preoperative and postoperative 24 hours",{"measure":32,"description":33,"timeFrame":30},"Infection indicators","Record the values of PCT, IL-6, and CRP of patients before and 24 hours after surgery",{"measure":35,"description":36,"timeFrame":17},"age",null,{"measure":38,"description":36,"timeFrame":17},"gender",{"measure":40,"description":36,"timeFrame":17},"Body Mass Index",{"measure":42,"description":43,"timeFrame":17},"diabetes","Record whether the patient has diabetes",{"measure":45,"description":46,"timeFrame":47},"enteral nutrition","Record the start time of enteral nutrition for patients after surgery.","The average observation time is 2 weeks after surgery.",{"measure":49,"description":50,"timeFrame":51},"Exhaust and defecation time","Record the time of the patient\\'s first exhaust and first bowel movement after surgery","The average observation time is one week after surgery",{"allocation":36,"interventionModel":36,"interventionModelDescription":36,"primaryPurpose":36,"observationalModel":53,"timePerspective":54,"maskingInfo":36},"CASE_CONTROL","PROSPECTIVE","People undergoing gastrointestinal surgery",[57,61],{"label":58,"type":36,"description":36,"interventionNames":59},"Intestinal barrier dysfunction group",[60],"Other: No intervention was carried out",{"label":62,"type":36,"description":36,"interventionNames":63},"Non-intestinal barrier dysfunction group",[60],[65],{"type":6,"name":66,"description":67,"armGroupLabels":68,"otherNames":36},"No intervention was carried out","This study is an observational study and no intervention was performed on the patients.",[58,62],[70],{"name":71,"role":72,"phone":73,"phoneExt":36,"email":74},"weiming Li","CONTACT","13114225597","liweiming49@163.com",{"type":76,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"PRINCIPAL_INVESTIGATOR","Weiming Li","Investigator","100561892",false,"NCT06596070","Clinical Study of Intestinal Barrier Dysfunction After Gastrointestinal Surgery","Clinical Study of Intestinal Barrier Dysfunction in Patients After Gastrointestinal Surgery","Inclusion Criteria:\n\n* men or women aged 18-80 years\n* expected feasible abdominal surgical treatment (partial gastrectomy, colorectal resection)\n* no preoperative intestinal barrier dysfunction\n* patients voluntarily participated in this study and signed an informed consent form.\n\nExclusion Criteria:\n\n* Patients or their families refused to participate in this study\n* chronic inflammatory diseases (e.g. inflammatory bowel disease, chronic hepatitis, chronic pancreatitis, chronic peptic ulcer, etc.)\n* history of antibiotic administration in the last 2 weeks\n* severe cognitive impairment and other inability to cooperate preoperative neoadjuvant radiotherapy\n* combined with severe hepatic, renal, and cardiac insufficiency patients.","ALL","18 Years","80 Years",{"count":89,"type":90},180,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to explore the clinical influences associated with the development of intestinal barrier dysfunction in patients undergoing gastrointestinal surgery. The main question it aims to answer is:What clinical factors increase the probability of developing intestinal barrier dysfunction in patients after gastrointestinal surgery?",[94],"Intestinal Barrier Dysfunction","NOT_YET_RECRUITING","2024-09-12",{"date":98,"type":99},"2024-09-19","ACTUAL",{"date":101,"type":90},"2024-10",{"date":103,"type":90},"2025-04",{"name":5,"class":6}]