About this trial
The study aims to obtain a local control rate in patients with lateral pelvic relapses of gynecologycal cancers previously irradiated. High LET (Linear Energy Transfer) particles as carbon ions can guarantee a biologic advantage compared to photons in radioresistant neoplasms, given to their higher biological efficacy (RBE).
Eligibility criteria
Qualifiers
Patients ≥ 18 years of age
Karnofsky Index ≥ 70
Histological or radiological diagnosis of pelvic and groin recurrence
Contraindications for radical surgery
Disqualifiers
Hip prosthesis, metal prostheses or any other condition that prevents adequate imaging to identify the target volume and calculate the dose in the treatment plan
Intestinal infiltration
Bladder infiltration
Vessel infiltration
Trial design
Treatments tested in this trial
- carbon ion radiation therapy
Treatment groups
Locations
1Sponsors and collaborators
CNAO National Center of Oncological Hadrontherapy
Lead sponsor