[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618792":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":18,"locations":24,"responsibleParty":37,"collaborators":10,"id":41,"slug":10,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":10,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":10,"enrollmentInfo":49,"targetDuration":10,"studyType":52,"phases":10,"briefSummary":53,"conditions":54,"keywords":10,"overallStatus":26,"whyStopped":10,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":65},{"fullName":5,"class":6},"Chinese Academy of Medical Sciences, Fuwai Hospital","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Cardiac Implantable Electronic Device Cohort",null,[12],"Other: Cardiac Magnetic Resonance Imaging",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":10},"Cardiac Magnetic Resonance Imaging","Cardiac magnetic resonance imaging performed as part of routine clinical care. Imaging data are used for observational research analyses only, without altering clinical management.",[9],[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Xinqiao Lian","CONTACT","18810639895","lxq010126@163.com",[25],{"facility":10,"status":26,"city":27,"state":10,"zip":10,"country":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"RECRUITING","Beijing","China",{"type":30,"coordinates":31},"Point",[32,33],116.39723,39.9075,{"lat":33,"lon":32},[36],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Minjie Lu","Principal Investigator","100618792",false,"NCT07336225","CMR-Based Prognostic Study in Patients With Cardiac Implantable Electronic Devices","Prognostic Value of Cardiovascular Magnetic Resonance in Patients With Cardiac Implantable Electronic Devices","Inclusion Criteria:\n\n1. Adult patients (≥18 years old).\n2. Patients with guideline-based indications for cardiac implantable electronic device (CIED) therapy, including pacemaker, implantable cardioverter-defibrillator, or cardiac resynchronization therapy.\n3. Patients who underwent cardiovascular magnetic resonance (CMR) imaging as part of routine clinical evaluation prior to CIED implantation or consideration of CIED therapy.\n\nExclusion Criteria:\n\n1. Patients younger than 18 years of age.\n2. Patients with non-diagnostic or poor-quality CMR images that preclude reliable image analysis.\n3. Patients with incomplete key clinical data or missing follow-up information for primary outcome assessment.\n4. Patients with prior heart transplantation or implantation of ventricular assist devices before CMR examination.\n5. Patients with congenital heart disease requiring surgical correction.","ALL","18 Years",{"count":50,"type":51},1500,"ESTIMATED","OBSERVATIONAL","Cardiac implantable electronic devices (CIEDs) are widely used to treat patients with heart failure, malignant arrhythmias, and other conditions. However, accurately identifying suitable candidates for CIED implantation remains a clinical challenge. Cardiovascular magnetic resonance imaging (CMR) provides a comprehensive assessment of cardiac structure, function, and tissue characteristics, facilitating evaluation of the myocardial substrate for arrhythmias. This study aims to evaluate the prognostic value of multiparametric CMR-derived imaging markers in CIED patients through preoperative CMR examinations. Imaging parameters of interest include structural-functional indices, myocardial strain, late gadolinium enhancement, entropy, and T1 and T2 mapping. Long-term clinical outcomes will be obtained from existing medical records and follow-up. The primary endpoint is sudden cardiac death (SCD) or SCD-equivalent events, defined as SCD, resuscitated cardiac arrest, sustained ventricular tachycardia or ventricular fibrillation, or appropriate ICD therapy. Secondary endpoints include all-cause mortality or heart failure rehospitalization. This study aims to elucidate the role of CMR in assessing CIED treatment indications and long-term risk stratification, thereby helping to optimize CIED implantation decisions.",[55],"Arrhythmias","2026-01-25",{"date":58,"type":59},"2026-01-27","ACTUAL",{"date":61,"type":59},"2010-01-01",{"date":63,"type":51},"2040-12-31",{"name":5,"class":6},1]