About this trial
The investigators are doing this study to learn more about how to prevent type 2 diabetes in teenage girls. The purpose of this study is to find out if taking part in a cognitive-behavioral therapy group, exercise training group, or a combination of cognitive-behavioral therapy and exercise training groups, decreases stress, improves mood, increases physical activity and physical fitness, and decreases insulin resistance among teenagers at risk for diabetes.
Eligibility criteria
Qualifiers
Female
Age 12-17 years
Body Mass Index (BMI)>= 85 for age and sex
Type 2 Diabetes (T2D) first-or second-degree relative
Disqualifiers
T2D/ Type 1 Diabetes (T1D) or any major medical condition (e.g. cardiovascular, renal) that would prohibit the ability to participate in exercise training
Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) conduct disorder, substance abuse/ dependence, obsessive compulsive disorder, panic attacks, post-traumatic stress disorder, anorexia/bulimia, & schizophrenia
Insulin sensitizers, weight loss medications & chronic steroids
Structured weight loss treatment or bariatric surgery
Trial design
Treatments tested in this trial
- Cognitive-Behavioral Therapy followed by Exercise Training
- Exercise Training followed by Cognitive-Behavioral Therapy
- Cognitive-Behavioral Therapy Only
- Exercise Training Only
Treatment groups
Locations
2Sponsors and collaborators
Colorado State University
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
University of Colorado, Denver
Collaborator