About this trial

This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction. All types of brain tumours apart from glioblastoma will be included.

Eligibility criteria

Qualifiers

18 years or older and Danish speaking.

Performance status WHO 0-2

Capable of cooperating on testing

Tumour histology (WHO 2016 classification) of the following types: anaplastic astrocytoma (IDH mutant), diffuse astrocytoma (IDH-mutant), gemistocytic astrocytoma (IDH mutant), diffuse astrocytoma (NOS), oligodendroglioma, meningioma, medulloblastoma (NOS), pituitary adenoma, other brain tumours including skull base sarcomas

Disqualifiers

Glioblastoma

Performance status 3-4 (Karnofsky Performances of 60 or less)

Trial design

Treatments tested in this trial

  • Cognitive tests and Patient Reported Outcomes

Treatment groups

No treatment groups listed

Locations

5
Department of Oncology, Rigshospitalet2100, CopenhagenCapital Region, Denmark
Danish Center for Particel Therapy8200, AarhusRegion Midt, Denmark
Department of Oncology, Aarhus University Hospital8200, AarhusRegion Midt, Denmark
Department of Oncology, Aalborg University Hospital9000, AalborgRegion Nord, Denmark

Sponsors and collaborators

University of Aarhus

Lead sponsor