[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100434531":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":35,"locations":41,"responsibleParty":63,"collaborators":66,"id":70,"slug":10,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":10,"eligibilityCriteria":74,"healthyVolunteers":71,"sex":75,"minAge":76,"maxAge":10,"enrollmentInfo":77,"targetDuration":10,"studyType":80,"phases":10,"briefSummary":81,"conditions":82,"keywords":10,"overallStatus":43,"whyStopped":10,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University of Oslo","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Brain abscess patients with cognitive dysfunction and\u002For fatigue",null,"This group of patients experience cognitive dysfunction and\u002For fatigue after brain abscess.",[13,14],"Other: FDG-PET","Other: EEG",{"label":16,"type":10,"description":17,"interventionNames":18},"Brain abscess patients without cognitive dysfunction and\u002For fatigue","This group of patients does not experience cognitive dysfunction and\u002For fatigue after brain abscess.",[13,14],[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"FDG-PET","\\[18F\\]Deoxyglucose-positron emission tomography at 0-10 years after brain abscess",[9,16],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"EEG","Electroencephalography (EEG) at 0-10 years after brain abscess",[9,16],[29,32],{"name":30,"affiliation":5,"role":31},"Bjørnar Hassel, MD, PhD","PRINCIPAL_INVESTIGATOR",{"name":33,"affiliation":34,"role":31},"Daniel Dahlberg, MD, PhD","Oslo University Hospital",[36],{"name":37,"role":38,"phone":39,"phoneExt":10,"email":40},"Peder H Utne","CONTACT","+4723066023","pedutn@ous-hf.no",[42],{"facility":34,"status":43,"city":44,"state":10,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Oslo","0450","Norway",{"type":48,"coordinates":49},"Point",[50,51],10.74609,59.91273,{"lat":51,"lon":50},[54,57,60],{"name":30,"role":38,"phone":55,"phoneExt":10,"email":56},"+4722118080","bjornar.hassel@medisin.uio.no",{"name":33,"role":38,"phone":58,"phoneExt":10,"email":59},"+4723070000","danieldahlberg@gmail.com",{"name":61,"role":62,"phone":10,"phoneExt":10,"email":10},"Ane G Rogne, Psychol.","SUB_INVESTIGATOR",{"type":31,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Bjørnar Hassel","Professor",[67,68],{"name":34,"class":6},{"name":69,"class":6},"Sunnaas Rehabilitation Hospital","100434531",false,"NCT04938362","Cognitive Function and Fatigue After Brain Abscess","Inclusion criteria:\n\n• Patients who have completed treatment for brain abscess and who agree to participate.\n\nExclusion criteria:\n\n* Patients who cannot undergo neuropsychological investigation due to unconsciousness\n* Patients who cannot undergo neuropsychological investigation, being mentally too ill\n* Patients who suffer from dementia\n* Patients who cannot undergo FDG-PET due to claustrophobia\n* Patients who cannot undergo EEG due to panic attacks\n* Age under 16.","ALL","16 Years",{"count":78,"type":79},50,"ESTIMATED","OBSERVATIONAL","Brain abscess is a focal bacterial or fungal infection of the brain. Treatment is neurosurgical drainage of pus followed by long-term antibiotic treatment. In spite of successful treatment of the infection, long-term cognitive problems or mental fatigue may ensue. The reason for this dysfunction may be a continuing inflammatory state or damage to brain tissue caused by the abscess. The investigators will evaluate these possibilities with the use of \\[18F\\]deoxyglucose-positron emission tomography (FDG-PET) and electroencephalography (EEG) in patients who have been treated for brain abscess and who experience cognitive problems and\u002For fatigue. FDG-PET may identify both inflammation and altered neuronal activity (the latter indicating damage to brain tissue), and EEG may identify altered neuronal activity, including changes in neuronal network activity.",[83,84,85],"Brain Abscess","Fatigue","Cognitive Dysfunction","2025-07-01",{"date":88,"type":89},"2025-07-04","ACTUAL",{"date":91,"type":89},"2020-01-01",{"date":93,"type":79},"2030-12-31",{"name":5,"class":6},1]