[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628696":3},{"organization":4,"outcomesModule":7,"designInfo":13,"detailedDescription":11,"studyPopulation":16,"armGroups":11,"interventions":11,"overallOfficials":11,"centralContacts":17,"locations":11,"responsibleParty":23,"collaborators":11,"id":25,"slug":11,"hasResults":26,"nctId":27,"briefTitle":28,"officialTitle":29,"acronym":11,"eligibilityCriteria":30,"healthyVolunteers":31,"sex":32,"minAge":11,"maxAge":11,"enrollmentInfo":33,"targetDuration":11,"studyType":36,"phases":11,"briefSummary":37,"conditions":38,"keywords":11,"overallStatus":41,"whyStopped":11,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":11},{"fullName":5,"class":6},"The Second Affiliated Hospital of Chongqing Medical University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":11,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"28-day all-cause mortality in cirrhosis with sepsis",null,"Baseline and 28 days.",{"allocation":11,"interventionModel":11,"interventionModelDescription":11,"primaryPurpose":11,"observationalModel":14,"timePerspective":15,"maskingInfo":11},"COHORT","RETROSPECTIVE","Cirrhosis complicated by sepsis",[18],{"name":19,"role":20,"phone":21,"phoneExt":11,"email":22},"Li ShiYing Deputy Chief Physician of the Department of Infectious Disease, Ph.D","CONTACT","0086+18623322462","302946@hospital.cqmu.edu.cn",{"type":24,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100628696",false,"NCT07465003","Cohort Study of Chronic Liver Disease Complicated by Sepsis","Use of Antimicrobial Drugs in Severe Infections and Epidemiological Study of Populations With Severe Infections","Inclusion Criteria:\n\n* Clinically or pathologically diagnosed with cirrhosis;\n* meets the Sepsis-3 diagnostic criteria.\n\nExclusion Criteria:\n\n* Combined organ transplantation, active malignant tumors;\n* Pregnant or breastfeeding women;\n* Long-term use of immunosuppressants (non-steroidal);\n* Death or voluntary discharge within 24 hours of admission;\n* Incomplete data.",true,"ALL",{"count":34,"type":35},1600,"ESTIMATED","OBSERVATIONAL","Study population: Patients with liver cirrhosis complicated by sepsis Observation indicators: Fluid resuscitation strategy, early dynamic indicators such as MAP Observation endpoint: 28-day all-cause mortality Study design: Retrospective cohort study",[39,40],"Cirrhosis","Sepsis","NOT_YET_RECRUITING","2026-03-09",{"date":44,"type":45},"2026-03-11","ACTUAL",{"date":47,"type":35},"2026-02-25",{"date":49,"type":35},"2028-06-01",{"name":5,"class":6}]