[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100536354":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":43,"centralContacts":47,"locations":54,"responsibleParty":72,"collaborators":76,"id":79,"slug":52,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":52,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":100,"overallStatus":57,"whyStopped":52,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Vail Health Behavioral Health","OTHER",[8,14,19,23],{"label":9,"type":10,"description":11,"interventionNames":12},"Depression + Whole Body Hyperthermia","ACTIVE_COMPARATOR","Participants experiencing depression will receive a single heat treatment using the Clearlight Sauna Dome lasting up to 140 minutes.",[13],"Procedure: Whole Body Hyperthermia",{"label":15,"type":10,"description":16,"interventionNames":17},"Depression + Whole Body Hyperthermia + Cold Water Plunge","Participants experiencing depression will receive a single heat session using the Clearlight Sauna Dome lasting up to 140 minutes followed by a cold plunge session lasting up to 10 minutes.",[13,18],"Procedure: Cold Water Plunge",{"label":20,"type":10,"description":21,"interventionNames":22},"No Depression + Whole Body Hyperthermia","Participants not experiencing depression will receive a single heat treatment using the Clearlight Sauna Dome lasting up to 140 minutes.",[13],{"label":24,"type":10,"description":25,"interventionNames":26},"No Depression + Whole Body Hyperthermia + Cold Water Plunge","Participants not experiencing depression will receive a single heat session using the Clearlight Sauna Dome lasting up to 140 minutes followed by a cold plunge session lasting up to 10 minutes.",[13,18],[28,36],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"PROCEDURE","Whole Body Hyperthermia","Participants in the heat exposure alone group will receive a single heat session using the Clearlight Sauna Dome lasting up to 140 minutes",[9,15,20,24],[34,35],"Infrared Sauna","Whole Body Heating",{"type":29,"name":37,"description":38,"armGroupLabels":39,"otherNames":40},"Cold Water Plunge","Participants in the heat exposure and cold plunge group will receive a single heat session using the Clearlight Sauna Dome lasting up to 140 minutes followed by a cold plunge session in 55 degree (Fahrenheit) water, lasting up to 10 minutes.",[15,24],[41,42],"Cold Plunge","Cold Water Exposure",[44],{"name":45,"affiliation":5,"role":46},"Barry Sandler, DO","PRINCIPAL_INVESTIGATOR",[48],{"name":49,"role":50,"phone":51,"phoneExt":52,"email":53},"Study Coordinator","CONTACT","970-855-7374",null,"BHIC@vailhealth.org",[55],{"facility":56,"status":57,"city":58,"state":59,"zip":60,"country":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"Vail Health Behavioral Health Innovation Center","RECRUITING","Edwards","Colorado","81632","United States",{"type":63,"coordinates":64},"Point",[65,66],-106.5942,39.64499,{"lat":66,"lon":65},[69,71],{"name":49,"role":50,"phone":70,"phoneExt":52,"email":53},"970-445-2489",{"name":45,"role":46,"phone":52,"phoneExt":52,"email":52},{"type":73,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":52,"oldOrganization":52},"SPONSOR_INVESTIGATOR","Barry Sandler","Medical Director of Vail Healthspan",[77],{"name":78,"class":6},"Steadman Philippon Research Institute","100536354",false,"NCT06263738","Cold and Heat Investigation to Lower Levels of Depression","CHILL'D","Inclusion Criteria:\n\n* Individuals who currently meet study criteria for depression or individuals who do not currently meet criteria for depression\n* English or Spanish speaking (able to provide informed consent and complete questionnaires in one of these languages)\n* Able and willing to adhere to trial requirements, including attending all trial visits, preparatory and follow-up sessions, and completing all trial evaluations.\n\nExclusion Criteria:\n\n* Previous adverse reaction to hypothermia, hyperthermia and\u002For infrared exposure\n* Use of any medication that may impact thermoregulatory capacity.\n* Pregnancy, active lactation, or intention to become pregnant during the study period.\n* Endorses current active suicidal ideation with a plan or made a suicide attempt in the prior 6 months.",true,"ALL","18 Years","65 Years",{"count":90,"type":91},162,"ESTIMATED","INTERVENTIONAL",[94],"NA","This study will recruit 112 medically healthy adults (aged 18-65) currently experiencing depressive symptoms to be randomized to receive either a single Whole Body Hyperthermia (heat therapy) treatment or a Whole Body Hyperthermia treatment followed by a cold water plunge. Participants will complete a baseline assessment of their depressive symptoms as well as 1-week and 2-week post-treatment followup assessments.",[97,98,99],"Depression","Mood Disorders","Healthy (Controls)",[97,98,101,102,103,104,41],"Mental Health","Integrative Health","Hyperthermia","Sauna","2025-11-11",{"date":107,"type":108},"2025-11-13","ACTUAL",{"date":110,"type":108},"2024-05-14",{"date":112,"type":91},"2027-04-01",{"name":74,"class":6},1]