[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100470831":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":25,"centralContacts":29,"locations":39,"responsibleParty":186,"collaborators":188,"id":192,"slug":10,"hasResults":193,"nctId":194,"briefTitle":195,"officialTitle":196,"acronym":10,"eligibilityCriteria":197,"healthyVolunteers":193,"sex":198,"minAge":199,"maxAge":10,"enrollmentInfo":200,"targetDuration":10,"studyType":203,"phases":10,"briefSummary":204,"conditions":205,"keywords":10,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":208,"lastUpdatePostDateStruct":209,"startDateStruct":212,"completionDateStruct":214,"leadSponsor":216,"locationsCount":217},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Observational (biospecimen collection, record review)",null,"Patients undergo collection of blood and stool samples no more than 90 days prior to or between 7-90 days after standard of care colonoscopy or flexible sigmoidoscopy. Patients' medical records are also reviewed.",[13,14],"Procedure: Biospecimen Collection","Other: Electronic Health Record Review",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"PROCEDURE","Biospecimen Collection","Undergo collection of blood and stool samples",[9],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"Electronic Health Record Review","Medical records reviewed",[9],[26],{"name":27,"affiliation":5,"role":28},"Niloy Jewel Samadder, M.D.","PRINCIPAL_INVESTIGATOR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"Rosalie Himle","CONTACT","507-266-5755","LaMere.Rosalie@mayo.edu",{"name":36,"role":32,"phone":37,"phoneExt":10,"email":38},"Clinical Trials Referral Office","855-776-0015","mayocliniccancerstudies@mayo.edu",[40,61,78,95,109,126,138,152,169],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Mayo Clinic in Arizona","RECRUITING","Scottsdale","Arizona","85259","United States",{"type":48,"coordinates":49},"Point",[50,51],-111.89903,33.50921,{"lat":51,"lon":50},[54,58,59],{"name":55,"role":32,"phone":56,"phoneExt":10,"email":57},"Colleen Gallagher","480-574-1346","gallagher.colleen@mayo.edu",{"name":36,"role":32,"phone":37,"phoneExt":10,"email":38},{"name":60,"role":28,"phone":10,"phoneExt":10,"email":10},"Jewel Samadder, M.D.",{"facility":62,"status":42,"city":63,"state":64,"zip":65,"country":46,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"University of California San Francisco","San Francisco","California","94115",{"type":48,"coordinates":67},[68,69],-122.41942,37.77493,{"lat":69,"lon":68},[72,76],{"name":73,"role":32,"phone":74,"phoneExt":10,"email":75},"Rachael Leigh Delacruz","415-514-8087","Rachaelleigh.delacruz@ucsf.edu",{"name":77,"role":28,"phone":10,"phoneExt":10,"email":10},"Aparajita Singh,, MD",{"facility":79,"status":42,"city":80,"state":81,"zip":82,"country":46,"cosmosGeoPoint":83,"geoPoint":87,"contacts":88},"University of Colorado Anschutz Medical Center","Aurora","Colorado","80045",{"type":48,"coordinates":84},[85,86],-104.83192,39.72943,{"lat":86,"lon":85},[89,93],{"name":90,"role":32,"phone":91,"phoneExt":10,"email":92},"Mahlet Haileyesus","303-724-6070","mahlet.haileyesus@cuanschutz.edu",{"name":94,"role":28,"phone":10,"phoneExt":10,"email":10},"Swati Patel, MD",{"facility":96,"status":42,"city":97,"state":98,"zip":99,"country":46,"cosmosGeoPoint":100,"geoPoint":104,"contacts":105},"Mayo Clinic in Florida","Jacksonville","Florida","32224",{"type":48,"coordinates":101},[102,103],-81.65565,30.33218,{"lat":103,"lon":102},[106,107],{"name":36,"role":32,"phone":37,"phoneExt":10,"email":38},{"name":108,"role":28,"phone":10,"phoneExt":10,"email":10},"Douglas L. Riegert-Johnson, MD",{"facility":110,"status":111,"city":112,"state":113,"zip":114,"country":46,"cosmosGeoPoint":115,"geoPoint":119,"contacts":120},"Beth Israel Deaconess Medical Center","NOT_YET_RECRUITING","Boston","Massachusetts","02215",{"type":48,"coordinates":116},[117,118],-71.05977,42.35843,{"lat":118,"lon":117},[121,125],{"name":122,"role":32,"phone":123,"phoneExt":10,"email":124},"Katharine Germansky, MD","617-667-5661","kgermans@bidmc.harvard.edu",{"name":122,"role":28,"phone":10,"phoneExt":10,"email":10},{"facility":127,"status":42,"city":112,"state":113,"zip":114,"country":46,"cosmosGeoPoint":128,"geoPoint":130,"contacts":131},"Dana Farber Cancer Institute",{"type":48,"coordinates":129},[117,118],{"lat":118,"lon":117},[132,136],{"name":133,"role":32,"phone":134,"phoneExt":10,"email":135},"Rachel Yore","857-215-2924","rachel_yore@dfci.harvard.edu",{"name":137,"role":28,"phone":10,"phoneExt":10,"email":10},"Sapna Syngal, MD, MPH",{"facility":5,"status":42,"city":139,"state":140,"zip":141,"country":46,"cosmosGeoPoint":142,"geoPoint":146,"contacts":147},"Rochester","Minnesota","55905",{"type":48,"coordinates":143},[144,145],-92.4699,44.02163,{"lat":145,"lon":144},[148,149,150],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},{"name":36,"role":32,"phone":37,"phoneExt":10,"email":38},{"name":151,"role":28,"phone":10,"phoneExt":10,"email":10},"John Kisiel, M.D.",{"facility":153,"status":42,"city":154,"state":155,"zip":156,"country":46,"cosmosGeoPoint":157,"geoPoint":161,"contacts":162},"University of Pennsylvania","Philadelphia","Pennsylvania","19104",{"type":48,"coordinates":158},[159,160],-75.16362,39.95238,{"lat":160,"lon":159},[163,167],{"name":164,"role":32,"phone":165,"phoneExt":10,"email":166},"Michaela Dungan","215-360-0833","michaela.dungan@pennmedicine.upenn.edu",{"name":168,"role":28,"phone":10,"phoneExt":10,"email":10},"Bryson Katona, MD, PhD",{"facility":170,"status":42,"city":171,"state":172,"zip":173,"country":46,"cosmosGeoPoint":174,"geoPoint":178,"contacts":179},"University of Washington","Seattle","Washington","98102",{"type":48,"coordinates":175},[176,177],-122.33207,47.60621,{"lat":177,"lon":176},[180,184],{"name":181,"role":32,"phone":182,"phoneExt":10,"email":183},"Brian Foerster","206-685-1179","bfoerster@medicine.washington.edu",{"name":185,"role":28,"phone":10,"phoneExt":10,"email":10},"William Grady, MD",{"type":187,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[189],{"name":190,"class":191},"Exact Sciences Corporation","INDUSTRY","100470831",false,"NCT05410977","Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients","Detection of Colorectal Cancer or Advanced Neoplasia by Stool DNA in Lynch Syndrome: CORAL Study","Inclusion Criteria:\n\n* Patients at least 18 years of age\n* Individuals diagnosed with Lynch syndrome (mutation in MLH1, MSH2, MSH6, PMS2, EPCAM) or colorectal cancer (CRC) with suspected Lynch syndrome or individuals diagnosed with early onset CRC (\\\u003C55 years old)\n* Colonoscopy\u002Fflexible sigmoidoscopy (flex sig) scheduled +\u002F- 90 days from sample collection\n* Patient has agreed to participate and has signed the study consent form\n\nExclusion Criteria:\n\n* Patient has known cancer (stage I-IV) within 5 years prior to current sample collection (not including basal cell or squamous cell skin cancers; if patient has not been seen or if information is not available, the patient is eligible)\n* Patient has received chemotherapy class drugs for the treatment of cancer in the 5 years prior to current sample collection\n* Patient has had any abdominal radiation therapy prior to current sample collection\n* Patient had therapy to the target (non-hyperplastic) lesion with intent to completely remove or debulk the lesion prior to sample collection \\[examples include snare polypectomy, endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), surgical resection, trans anal excision\\]\n* Patient has prior diagnosis of non-lynch hereditary colon cancer syndrome \\[familial adenomatous polyposis (FAP), MUTYH-associated polyposis (MAP), Peutz-Jeghers syndrome (PJS), juvenile polyposis syndrome (JPS), PTEN, POL\\]\n* ADDITIONAL STOOL EXCLUSIONS:\n* Bowel prep \\\u003C7 days prior to stool collection\n* Oral or rectal contrast given within 7 days prior to stool collection\n* Presence of ileostomy\n* Enteral feeds or total parenteral nutrition (TPN)\n* Diagnosis of inflammatory bowel disease","ALL","18 Years",{"count":201,"type":202},950,"ESTIMATED","OBSERVATIONAL","This study collects blood and stool samples from patients with suspected or diagnosed Lynch syndrome to evaluate a deoxyribonucleic acid (DNA) screening technique for the detection of colorectal cancer in Lynch syndrome patients.",[206,207],"Colorectal Carcinoma","Lynch Syndrome","2026-05-22",{"date":210,"type":211},"2026-05-27","ACTUAL",{"date":213,"type":211},"2022-03-30",{"date":215,"type":202},"2027-12-31",{"name":5,"class":6},9]