Health Trials

About this trial

This is a cross-sectional study aimed at identifying factors which best predicts patients at high risk of colorectal cancer or colorectal adenomas and to develop a risk prediction model.

Eligibility criteria

Qualifiers

Aged ≥30 years* and able to give informed consent

Patients attending colonoscopy

Through Bowel Cancer Screening Programme (FIT positive, Bowelscope conversion, surveillance)

Through standard NHS care (most commonly due to iron deficiency anaemia, altered bowel habit, weight loss, rectal bleeding, planned polypectomy**, those referred on basis of family history, abnormal cross-sectional imaging, polyp surveillance or post CRC surveillance)

Disqualifiers

Unable to give informed consent

Known polyposis syndrome

Previous total colectomy

Known colonic stricture which would limit complete colonoscopy

Trial design

Treatments tested in this trial

  • Colonoscopy

Treatment groups

15,000 Participants
are divided into 2 treatment groups

Locations

3
South Tyneside and Sunderland NHS Foundation TrustNE34 0PL, South ShieldsTyne and Wear, United Kingdom
Kettering General Hospitals NHS Foundation TrustNN16 8UZ, Kettering United Kingdom
North Tees and Hartlepool NHS Foundation TrustTS19 8PE, Stockton-on-Tees United Kingdom

Sponsors and collaborators

South Tyneside and Sunderland NHS Foundation Trust

Lead sponsor

Newcastle University

Collaborator

Source ClinicalTrials.gov