[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100544488":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":64,"collaborators":26,"id":66,"slug":26,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":26,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":83,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University Hospital, Ghent","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active tDCS group","ACTIVE_COMPARATOR","Patients will receive active tDCS during the therapy.",[13],"Device: Active tDCS",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham tDCS group","SHAM_COMPARATOR","Patients will receive sham tDCS during the therapy.",[19],"Device: Sham tDCS",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Active tDCS","During the whole therapy period, active tDCS group will receive active tDCS after CBT. They also receive active home-based tDCS.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham tDCS","The sham tDCS group will receive sham tDCS after CBT. They also receive sham home-based tDCS.",[15],[32],{"name":33,"affiliation":34,"role":35},"Chris Baeken","University Ghent","PRINCIPAL_INVESTIGATOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+32476209841","Chris.Baeken@ugent.be",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":44},"Sara De Witte","+32498382824","sara.dewitte@ugent.be",[46],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"University Hospital Ghent","RECRUITING","Ghent","East-Flanders","9000","Belgium",{"type":54,"coordinates":55},"Point",[56,57],3.71667,51.05,{"lat":57,"lon":56},[60,62],{"name":61,"role":38,"phone":26,"phoneExt":26,"email":26},"Chris Baeken, Prof.",{"name":63,"role":38,"phone":26,"phoneExt":26,"email":26},"Josefien Dedoncker, M.Sc.",{"type":65,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100544488",false,"NCT06369532","Combination of Neurostimulation and Psychotherapy to Stop Worrying","Stop Worrying, Learn to Let go Through a Combination of Neurostimulation and Psychotherapy","Inclusion Criteria:\n\n* Generalized anxiety disorder (GAD)\n* Depressive disorder\n\nExclusion Criteria:\n\n* other psychiatric pathology than GAD or depression screened by senior psychiatrist by means of the Mini-International Neuropsychiatric Interview (MINI) and psychiatric anamnesis\n* Abuse of alcohol, drugs or medication other than prescribed by general practitioner or psychiatrist\n* no consent to participate in measurement (questionnaire, fNIRS or EEG)\n* Insufficient knowledge of the current language (Dutch)\n* Acute or chronic suicidality\n* Acute psychosis or manic depressive disorder\n* Inability to commit to 8 sessions of Cognitive-Behavioral Therapy (CBT) or receive 4 weeks of transcranial Direct Current Stimulation (tDCS).","ALL","18 Years","70 Years",{"count":76,"type":77},85,"ESTIMATED","INTERVENTIONAL",[80],"NA","This study aims to investigate whether the combination of transcranial Direct Current Stimulation (tDCS) and cognitive-behavioral therapy (CBT) is more effective for treating repetitive negative thinking (RNT) in patients with the symptom of high rumination. High ruminators will be included (Group1, active tDCS-CBT group; Group2, sham tDCS-CBT group). All patients will receive active or sham tDCS.",[23,28],[84],"transcranial direct current stimulation","2026-03-11",{"date":87,"type":88},"2026-03-12","ACTUAL",{"date":90,"type":88},"2024-03-06",{"date":92,"type":77},"2027-12-20",{"name":5,"class":6},1]