About this trial

In Mongolia, mortality from hepatocellular carcinoma (HCC) is one of the highest in the world. Viral hepatitis is the main cause of HCC: the prevalence of hepatitis B (HBV) estimated at 11% In Mongolia, hepatitis C (HCV) at 8.5%, and hepatitis Delta (HDV) at 40-60% in HBV-infected patients. Viral hepatitis are essentially asymptomatic and therefore require systematic screening for diagnosis. Once a diagnosis of chronic viral infection has been established, specific therapies are available to reduce the morbidity and mortality of these patients. A study carried out in California in the Mongolian community found an HBV prevalence of 9.7% and positive HDV serology in 41% of these patients.

There is a large Mongolian community in France, estimated at between 5,000 and 6,000 patients. Although the majority of these patients are covered by French social security; however, access to care and screening for viral hepatitis often remain difficult and insufficient for migrant or vulnerable populations in France The aim of this study is to screen the Mongolian community in France for viral hepatitis, and then initiate a program of care and treatment.

Eligibility criteria

Qualifiers

Mongolian people

Over 15 years of age

Living in France

Majors agree to participate or minors whose parental guardians agree to their child's participation in the study

Disqualifiers

People already followed for viral hepatitis, treated or not treated

Persons deprived of their liberty by a judicial or administrative decision

Adults subject to a legal protection measure (guardianship, curators)

People participate in any interventional research except routine care research (old regulation) and category 2 research that does not interfere with the primary endpoint analysis

Trial design

Treatments tested in this trial

  • Community screening for hepatitis B, C and delta in the Mongolian population living in France

Treatment groups

2,000 Participants
are divided into 1 treatment group

Locations

11
Centre Hospitalier Annecy Genevois Annecy France
Centre Expert Hépatites Virales Aquitaine, CHU de Bordeaux Bordeaux France
CHU de Clermont Ferrand Clermont-Ferrand France
Hôpital Henri Mondor - Assistante Publique Hopitaux de Paris (APHP) Créteil France

Sponsors and collaborators

Hospices Civils de Lyon

Lead sponsor