[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597566":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":31,"locations":42,"responsibleParty":53,"collaborators":30,"id":57,"slug":30,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":30,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":30,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":76,"whyStopped":30,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A","ACTIVE_COMPARATOR","left side of face the patient will be given resveratrol 1 % gel once daily at night (homThee use ).",[13],"Drug: resveratrol 1 % gel",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B","The right side of face will treated with TCA20% every two weeks for 3months.",[18],"Drug: TCA20%",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","resveratrol 1 % gel","left side of face the patient will be given resveratrol 1 % gel once daily at night (Home use ).",[9],[26],"1",{"type":21,"name":28,"description":11,"armGroupLabels":29,"otherNames":30},"TCA20%",[15],null,[32,38],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"amira mohamed bakry, Resident doctor of Dermatology","CONTACT","+201014524304","+201050007566","amirakedwany@icloud.com",{"name":39,"role":34,"phone":40,"phoneExt":30,"email":41},"Dalia Abdel-Aziz Ahmed Attallah, Professor of Dermatology","+201005677229","daliaattallah@aun.edu.eg",[43],{"facility":44,"status":30,"city":45,"state":30,"zip":30,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":30},"Assuit","Asyut","Egypt",{"type":48,"coordinates":49},"Point",[50,51],31.18368,27.18096,{"lat":51,"lon":50},{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Amira Mohamed Bakry Refaay","doctor","100597566",false,"NCT07060157","Comparative Efficacy of Resveratrol 1 % Gel and Trichloroacetic Acid 20% in Treatment of Melasma: A Split-face Study","Inclusion Criteria:\n\n* • Age: 18-50 years old.\n\n  * Pattern of melasma: Bilateral symmetrical facial melasma of any pattern.\n  * Fitzpatrick skin phototypes: Types III, IV and V.\n\nExclusion Criteria:\n\n* Pregnancy and lactation.\n\n  * Patients taking oral contraceptive pills, hormonal replacement therapy or treatment for chronic illness at the time of the study or during the past 6 months.\n  * Coexistence of diseases associated with hyperpigmentation such as Addison disease.\n  * History of Scarring and keloid tendency\n  * Active skin infections as active HSV.\n  * Previous history of post- inflammatory hyperpigmentation.","ALL","18 Years","50 Years",{"count":66,"type":67},41,"ESTIMATED","INTERVENTIONAL",[70],"NA","1. To evaluate the efficacy and safety of topical resveratrol 1 % gel in treatment of melasma.\n2. To compare between the efficacy of topical resveratrol 1 %gel versrs chemical peeling with TCA 20% in melasma.",[73],"Melasma",[75],"resveratrol in melasma","NOT_YET_RECRUITING","2025-07-09",{"date":79,"type":80},"2025-07-11","ACTUAL",{"date":82,"type":67},"2025-07-22",{"date":84,"type":67},"2027-06-08",{"name":5,"class":6},1]