Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor

ConditionsPreterm Labor With Preterm Delivery Premature Rupture of Membranes Prolonged

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexFemale

Age18-48

SponsorWestern Galilee Hospital-Nahariya

About this trial

This randomized prospective trial aimed to compare 2 prophylactic antibiotic regiment (ampicillin alone versus ampicillin plus gentamycin) in term prolonged pre-labor rupture of membrane and in preterm deliveries and examine related obstetrical outcome and infectious morbidity

Eligibility criteria

Qualifiers

None

Disqualifiers

GBS carrier

preterm premature rupture of membrane for conservative treatment

intra-uterine fetal death fetal major anomaly

drug allergy for the antibiotic in use in this study

Trial design

Treatments tested in this trial

Ampicillin Only Product
ampicillin plus gentamicin

Treatment groups

600 Participants

are divided into 2 treatment groups

Locations

Galil Medical Center Nahariya Israel

Sponsors and collaborators

Western Galilee Hospital-Nahariya

Lead sponsor

Source ClinicalTrials.gov