[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100475365":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":51,"collaborators":25,"id":55,"slug":25,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":25,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Western Galilee Hospital-Nahariya","OTHER_GOV",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"women with term prolonged>18h rupture of membrane","ACTIVE_COMPARATOR","women with term prolonged \\>18 h prom or in preterm delivery will be treated with IV ampicillin 2 gr every 6 hours until delivery",[13,14],"Drug: Ampicillin Only Product","Drug: ampicillin plus gentamicin",{"label":16,"type":10,"description":17,"interventionNames":18},"women with preterm labor","women with term prolonged \\>18 h prom or in preterm delivery will be treated with IV ampicillin 2 gr every 6 hours until delivery plus IV gentamicin 5 mg\u002Fkg every 24 hours",[13,14],[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Ampicillin Only Product","women will be randomize to receive Ampicillin Only Product or ampicillin plus gentamicin",[16,9],null,{"type":21,"name":27,"description":23,"armGroupLabels":28,"otherNames":25},"ampicillin plus gentamicin",[16,9],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Maya Wolf, MD","CONTACT","972-50-7887800","mayaw@gmc.gov.il",[36],{"facility":37,"status":38,"city":39,"state":25,"zip":25,"country":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Galil Medical Center","RECRUITING","Nahariya","Israel",{"type":42,"coordinates":43},"Point",[44,45],35.09814,33.00892,{"lat":45,"lon":44},[48],{"name":31,"role":32,"phone":49,"phoneExt":25,"email":50},"972-507887800","homesickid@yahoo.com",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Dr. Maya Wolf","Director- Fetal Maternal Medicine Unit","100475365",false,"NCT05469984","Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor","Comparing Obstetrical Outcomes and Infectious Morbidity Between Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor","Inclusion Criteria: maternal age \\> 18 years singleton pregnancy vertex presentation prolonged \\>18 h prom or preterm delivery\n\n\\-\n\nExclusion Criteria:\n\n* GBS carrier\n* preterm premature rupture of membrane for conservative treatment\n* intra-uterine fetal death fetal major anomaly\n* drug allergy for the antibiotic in use in this study\n* women receiving antibiotic treatment for other infection such as urinary tract infection",true,"FEMALE","18 Years","48 Years",{"count":66,"type":67},600,"ESTIMATED","INTERVENTIONAL",[70],"NA","This randomized prospective trial aimed to compare 2 prophylactic antibiotic regiment (ampicillin alone versus ampicillin plus gentamycin) in term prolonged pre-labor rupture of membrane and in preterm deliveries and examine related obstetrical outcome and infectious morbidity",[73,74],"Preterm Labor With Preterm Delivery","Premature Rupture of Membranes Prolonged",[76,77,78,79,80],"prolonged term PROM","pre-term labor","prophylactic antibiotic","peripartum infection","bacterial distribution","2025-08-05",{"date":83,"type":84},"2025-08-06","ACTUAL",{"date":86,"type":84},"2022-11-25",{"date":88,"type":67},"2025-09-26",{"name":5,"class":6},1]