Health Trials

About this trial

This study includes patients diagnosed with proximal gastric cancer (Siewert type II/III, cT1-3N0-1M0) across six tertiary hospitals, who underwent either double-tract reconstruction (DTR) or tubular gastric anastomosis (TGA). Participants were divided into two groups based on the surgical procedure. We conducted a comparative analysis of postoperative outcomes by evaluating electronic medical records, postoperative gastroscopy, 24-hour esophageal pH monitoring, and relevant rating scales.

Eligibility criteria

Qualifiers

Pathologically confirmed gastric adenocarcinoma by biopsy

Carcinoma of the upper gastric body or Siewert type II/III adenocarcinoma of the esophagogastric junction (AEG), with a clinical stage of cT1-3N0-1M0

Age 18-75 years, with a performance status (PS) score of 0-2

Candidates for planned surgical resection, eligible for either double-tract reconstruction or tubular gastric anastomosis based on preoperative assessment

Disqualifiers

Presence of other malignant tumors or severe chronic diseases (e.g., severe diabetes mellitus, chronic kidney disease, decompensated cirrhosis, etc.)

Preoperative endoscopic diagnosis of Barrett's esophagus

Severe preoperative malnutrition (albumin <30 g/L, prealbumin <150 mg/L)

History of prior upper abdominal surgery, gastrointestinal malformation, or psychiatric disorders

Trial design

Treatments tested in this trial

  • Double-tract reconstruction

Treatment groups

52 Participants
are divided into 2 treatment groups

Locations

1
Qilu Hospital of Shandong University250012, JinanShandong, China

Sponsors and collaborators

Qilu Hospital of Shandong University

Lead sponsor

Source ClinicalTrials.gov