[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584416":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":38,"collaborators":26,"id":42,"slug":26,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":26,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":49,"maxAge":26,"enrollmentInfo":50,"targetDuration":26,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":61,"overallStatus":68,"whyStopped":26,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":26},{"fullName":5,"class":6},"Benha University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Flexible & Navigable Suction Ureteral Access Sheath (FANS) Group","EXPERIMENTAL","Patients in this group will undergo retrograde flexible ureteroscopy (FURS) with the Flexible \\& Navigable Suction Ureteral Access Sheath (FANS). The FANS facilitates continuous suctioning, improving stone fragment evacuation, reducing intrarenal pressure, and optimizing stone-free rates (SFR).",[13],"Procedure: Flexible & Navigable Suction Ureteral Access Sheath (FANS)",{"label":15,"type":16,"description":17,"interventionNames":18},"Antegrade Suction with Flexible Ureteroscopy (FURS) Group","ACTIVE_COMPARATOR","Patients in this group will undergo retrograde flexible ureteroscopy (FURS) with antegrade suction, using a percutaneous nephrostomy (PCN) access for suctioning from the kidney during the procedure. This method aims to enhance stone fragment clearance and reduce intrarenal pressure without using a ureteral access sheath.",[19],"Procedure: Antegrade Suction via Percutaneous Nephrostomy",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Flexible & Navigable Suction Ureteral Access Sheath (FANS)","The Flexible \\& Navigable Suction Ureteral Access Sheath (FANS) is used during retrograde flexible ureteroscopy (FURS) for renal stones (1.5-2 cm). It allows continuous active suctioning, improving stone fragment evacuation, reducing operative time, lowering intrarenal pressure, and optimizing stone-free rates (SFR). The procedure involves inserting the Navigator 10F, 55 cm YIGAOMED FANS over a guidewire, followed by flexible ureteroscopy with PUSEN® 9.2 Fr ureteroscope and laser lithotripsy using Holmium Laser (JenaSurgical® MultiPulse HoPLUS™ 150W).",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Antegrade Suction via Percutaneous Nephrostomy","This technique involves antegrade suction from the kidney during flexible ureteroscopy (FURS) without the use of a ureteral access sheath. A percutaneous nephrostomy (PCN) tract is created using an 18G needle, and a 6F renal dilator is placed and fixed to the skin, allowing for direct suctioning from the collecting system. Following this, retrograde flexible ureteroscopy (FURS) is performed using the PUSEN® 9.2 Fr ureteroscope and Holmium Laser (JenaSurgical® MultiPulse HoPLUS™ 150W) for stone fragmentation. This technique aims to improve stone clearance while minimizing ureteral trauma associated with access sheaths.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Tamer Diab, MD","CONTACT","01003583264","+2","tamer.diab@fmed.bu.edu.eg",{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Tamer Abd El-Wahab Diab","Lecturer of Urology, Faculty of Medicine.","100584416",false,"NCT06889051","Comparison of Flexible & Navigable Suction Ureteral Access Sheath vs. Antegrade Suction in Retrograde Flexible Ureteroscopy for Lower Calyceal Stones","Comparison Study Between Using Retrograde Flexible Ureteroscopy With Flexible & Navigable Suction Ureteral Access Sheath Versus Retrograde Flexible Ureteroscopy With Antegrade Suction in Lower Calyceal Stone: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult patients (≥18 years old)\n* Patients diagnosed with renal stones (1.5-2 cm) confirmed by non-contrast computed tomography (NCCT)\n* Patients undergoing flexible ureteroscopy (FURS) as the primary treatment approach\n* Patients with no active urinary tract infection (UTI) at baseline\n* Patients who provide written informed consent\n\nExclusion Criteria:\n\n* Patients with anatomical anomalies (e.g., horseshoe kidney, PUJ obstruction)\n* Patients with a single functioning kidney\n* Pregnant women\n* Patients with a history of urological malignancy\n* Patients with active bleeding disorders or those on anticoagulant therapy that cannot be safely discontinued\n* Patients at high risk for anesthesia","ALL","18 Years",{"count":51,"type":52},120,"ESTIMATED","INTERVENTIONAL",[55],"NA","This randomized controlled trial aims to compare the efficacy and safety of two suction techniques during retrograde flexible ureteroscopy (FURS) for lower calyceal renal stones measuring 1.5-2 cm. The study evaluates Flexible \\& Navigable Suction Ureteral Access Sheath (FANS) versus Antegrade Suction (via percutaneous access) in improving stone-free rates (SFR), reducing operative time, and minimizing complications such as bleeding, ureteral injury, and infection. A total of 120 adult patients will be randomized into two groups, undergoing either flexible ureteroscopy (FURS) with Flexible \\& Navigable Suction Ureteral Access Sheath (FANS) or flexible ureteroscopy (FURS) with antegrade suction, at Banha University Faculty of Medicine.",[58,59,60],"Nephrolithiasis","Urolithiasis","Endourology",[62,63,64,65,66,67],"Flexible Ureteroscopy (FURS)","Ureteral Access Sheath (UAS)","Suction Ureteral Access Sheath (FANS)","Antegrade Suction","Percutaneous Nephrostomy (PCN)","Laser Lithotripsy","NOT_YET_RECRUITING","2025-03-15",{"date":71,"type":72},"2025-03-21","ACTUAL",{"date":74,"type":52},"2025-03-30",{"date":76,"type":52},"2026-03-30",{"name":5,"class":6}]