[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100261164":3},{"organization":4,"outcomesModule":7,"designInfo":44,"detailedDescription":53,"studyPopulation":11,"armGroups":54,"interventions":86,"overallOfficials":106,"centralContacts":110,"locations":115,"responsibleParty":140,"collaborators":11,"id":143,"slug":11,"hasResults":144,"nctId":145,"briefTitle":146,"officialTitle":146,"acronym":147,"eligibilityCriteria":148,"healthyVolunteers":144,"sex":149,"minAge":150,"maxAge":151,"enrollmentInfo":152,"targetDuration":11,"studyType":155,"phases":156,"briefSummary":158,"conditions":159,"keywords":161,"overallStatus":118,"whyStopped":11,"lastUpdateSubmitDate":164,"lastUpdatePostDateStruct":165,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":173},{"fullName":5,"class":6},"Wenzhou Medical University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":34,"otherOutcomes":11},[9,13,15,18,21,24,26,28,30,32],{"measure":10,"description":11,"timeFrame":12},"Uncorrected Visual Acuity (UCVA) at Distance, Near",null,"3 months after surgery",{"measure":14,"description":11,"timeFrame":12},"Best distance corrected Visual Acuity at Distance, Near",{"measure":16,"description":17,"timeFrame":12},"Defocus curve","measured with distance correction for unilateral and bilateral",{"measure":19,"description":20,"timeFrame":12},"Contrast sensitivity","measured with CSV-1000HGT(VECTOR VISION, Greenville, OH)",{"measure":22,"description":23,"timeFrame":12},"Ocular aberration","measured with a custom-built aberrometer",{"measure":25,"description":11,"timeFrame":12},"Ocular Scatter Index measured by Optical Quality Analysis System(OQAS) II",{"measure":27,"description":11,"timeFrame":12},"Modulation Transfer Function (MTF) cut-off measured by OQAS II",{"measure":29,"description":11,"timeFrame":12},"Strehl Ratio measured by OQAS II",{"measure":31,"description":11,"timeFrame":12},"Quality of Vision (QoV) Questionnaire score",{"measure":33,"description":11,"timeFrame":12},"Catquest- 9SF Questionnaire score",[35,37,40,42],{"measure":36,"description":11,"timeFrame":12},"Refractive error after surgery",{"measure":38,"description":11,"timeFrame":39},"Rate of Posterior Capsule Opacification","6 months after surgery",{"measure":41,"description":11,"timeFrame":39},"Rate of Nd:YAG Laser Posterior Capsulotomy",{"measure":43,"description":11,"timeFrame":39},"Rate of Spectacle Independence",{"allocation":45,"interventionModel":46,"interventionModelDescription":11,"primaryPurpose":47,"observationalModel":11,"timePerspective":11,"maskingInfo":48},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":49,"maskingDescription":11,"whoMasked":50},"DOUBLE",[51,52],"PARTICIPANT","OUTCOMES_ASSESSOR","This study is a prospective randomized controlled trial to compare and evaluate the clinical outcomes of 6 kinds of Multifocal Intraocular Lenses, the outcome measurements include postoperative visual acuity, visual quality and complications. Patients enrolled in the study will be randomized to receive one of the Multifocal Intraocular Lenses mentioned above, and the clinical outcomes of each Multifocal Intraocular Lens will be assessed at several visits: 1 day, 1 week, 1 month, 3 months and months post-operatively.",[55,61,66,71,76,81],{"label":56,"type":57,"description":58,"interventionNames":59},"SN6AD1 group","ACTIVE_COMPARATOR","Bilateral cataract surgery with implantation of SN6AD1 multifocal IOLs",[60],"Device: SN6AD1",{"label":62,"type":57,"description":63,"interventionNames":64},"SBL-3 group","Bilateral cataract surgery with implantation of SBL-3 multifocal IOLs",[65],"Device: SBL-3",{"label":67,"type":57,"description":68,"interventionNames":69},"LS-313 MF30 group","Bilateral cataract surgery with implantation of LS-313 MF30 multifocal IOLs",[70],"Device: LS-313 MF30",{"label":72,"type":57,"description":73,"interventionNames":74},"AT LISA tri 839 MP group","Bilateral cataract surgery with implantation of AT LISA tri 839 MP multifocal IOLs",[75],"Device: AT LISA tri 839 MP",{"label":77,"type":57,"description":78,"interventionNames":79},"ART group","Bilateral cataract surgery with implantation of ART toric multifocal IOLs",[80],"Device: ART",{"label":82,"type":57,"description":83,"interventionNames":84},"LS-313 MF30T group","Bilateral cataract surgery with implantation of LS-313 MF30T toric multifocal IOLs",[85],"Device: LS-313 MF30T",[87,91,94,97,100,103],{"type":88,"name":89,"description":58,"armGroupLabels":90,"otherNames":11},"DEVICE","SN6AD1",[56],{"type":88,"name":92,"description":63,"armGroupLabels":93,"otherNames":11},"SBL-3",[62],{"type":88,"name":95,"description":68,"armGroupLabels":96,"otherNames":11},"LS-313 MF30",[67],{"type":88,"name":98,"description":73,"armGroupLabels":99,"otherNames":11},"AT LISA tri 839 MP",[72],{"type":88,"name":101,"description":78,"armGroupLabels":102,"otherNames":11},"ART",[77],{"type":88,"name":104,"description":83,"armGroupLabels":105,"otherNames":11},"LS-313 MF30T",[82],[107],{"name":108,"affiliation":5,"role":109},"AYong Yu, MD. PhD.","PRINCIPAL_INVESTIGATOR",[111],{"name":108,"role":112,"phone":113,"phoneExt":11,"email":114},"CONTACT","+86-0577-88068880","yaybetter@hotmail.com",[116],{"facility":117,"status":118,"city":119,"state":120,"zip":121,"country":122,"countryCode":123,"cosmosGeoPoint":124,"geoPoint":129,"contacts":130},"The Eye Hispital of Wenzhou Medical University","RECRUITING","Wenzhou","Zhejiang","325000","China","CN",{"type":125,"coordinates":126},"Point",[127,128],120.66682,27.99942,{"lat":128,"lon":127},[131,135,138],{"name":132,"role":112,"phone":133,"phoneExt":11,"email":134},"Anpeng Pan, MD.OD.","+86-577-88068809","pananpeng@126.com",{"name":136,"role":137,"phone":11,"phoneExt":11,"email":11},"Shuangqian Zhu, MD.","SUB_INVESTIGATOR",{"name":139,"role":137,"phone":11,"phoneExt":11,"email":11},"Kaijing Zhou, MD.PhD.",{"type":109,"investigatorFullName":141,"investigatorTitle":142,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"A-Yong Yu","Clinical Professor","100261164",false,"NCT02678962","Comparison of Outcomes With Multifocal Intraocular Lenses","COMIL","Inclusion Criteria:\n\n* Age from 40 to 80 years old, either gender;\n* Patients with bilateral age related cataracts, require bilateral cataract phacoemulsification combined Intraocular Lens implantation;\n* Willing to undergo second eye surgery within 7 days after first eye surgery;\n* The potential postoperative visual acuity of 20\u002F40 or better in both eyes;\n* Preoperative measurement of corneal astigmatism indicate the subjects are suitable for multifocal intraocular lenses implantation;\n* Capability to understand the informed consent and willing and able to attend study\n\nExclusion Criteria:\n\n* Preexisting ocular diseases or conditions other than age related cataracts, have contraindications for cataract surgery;\n* Preexisting systemic diseases or conditions that may confound the results of the study;\n* Previous ocular surgery history or ocular trauma that may confound the results of the study;\n* Require combined surgery that may confound the results of the study;\n* Previous participation in other clinical trial within 30 days of this study start;\n* Systemic or ocular medications that may confound the outcome of the intervention\n* Pregnant, lactating, or planning to become pregnant during the course of the trial;","ALL","40 Years","80 Years",{"count":153,"type":154},90,"ESTIMATED","INTERVENTIONAL",[157],"NA","The purpose of this study is to compare and evaluate the clinical outcomes of 6 kinds of Multifocal Intraocular Lenses: SN6AD1, SBL-3, LS-313 MF30, AT LISA tri 839 MP, ART, LS-313 MF30T.",[160],"Cataract",[162,163],"Multifocal Intraocular Lenses","bilateral implantation","2024-07-22",{"date":166,"type":167},"2024-07-23","ACTUAL",{"date":169,"type":11},"2016-02",{"date":171,"type":154},"2026-06",{"name":5,"class":6},1]