[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555613":3},{"organization":4,"outcomesModule":7,"designInfo":47,"detailedDescription":46,"studyPopulation":46,"armGroups":56,"interventions":68,"overallOfficials":46,"centralContacts":76,"locations":82,"responsibleParty":100,"collaborators":46,"id":104,"slug":46,"hasResults":105,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":46,"eligibilityCriteria":109,"healthyVolunteers":105,"sex":110,"minAge":111,"maxAge":46,"enrollmentInfo":112,"targetDuration":46,"studyType":115,"phases":116,"briefSummary":118,"conditions":119,"keywords":123,"overallStatus":85,"whyStopped":46,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":136},{"fullName":5,"class":6},"Germans Trias i Pujol Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":29,"otherOutcomes":46},[9,13,16,19,21,23,24,27,28],{"measure":10,"description":11,"timeFrame":12},"Pain at rest","Measured by the numerical visual scale at 6 hours after intradural anesthesia, minimum of 0 and maximum of 10, where means no pain and 10 means the worst pain in the life of the patient.","6 hours after surgery",{"measure":10,"description":14,"timeFrame":15},"Measured by the numerical visual scale at 24 hours after intradural anesthesia, minimum of 0 and maximum of 10, where means no pain and 10 means the worst pain in the life of the patient.","24 hours after surgery",{"measure":10,"description":17,"timeFrame":18},"Measured by the numerical visual scale at 48 hours after intradural anesthesia, minimum of 0 and maximum of 10, where means no pain and 10 means the worst pain in the life of the patient.","48 hours after surgery",{"measure":20,"description":17,"timeFrame":12},"Pain at movement",{"measure":22,"description":17,"timeFrame":15},"Pain with movement",{"measure":22,"description":17,"timeFrame":18},{"measure":25,"description":26,"timeFrame":12},"Motor block","Measured on a scale of 3, where 0 = no motor block, 1 = partial motor block and 2 = complete motor block. It will be performed on plantar flexion (distribution of the tibial nerve) and dorsiflexion (peroneal distribution)).",{"measure":25,"description":26,"timeFrame":15},{"measure":25,"description":26,"timeFrame":18},[30,33,34,35,39,42],{"measure":31,"description":32,"timeFrame":12},"Opioids dose","Measured in milligrams of intravenous morphine hydrochloride daily.",{"measure":31,"description":32,"timeFrame":15},{"measure":31,"description":32,"timeFrame":18},{"measure":36,"description":37,"timeFrame":38},"Discharge days","Time to discharge measured in days","Days",{"measure":40,"description":41,"timeFrame":15},"Patient satisfaction","Patient satisfaction on a scale of 0 to 10, where 0 is minimum satisfaction and 10 is maximum satisfaction.",{"measure":43,"description":44,"timeFrame":45},"Ambulation time","Time to ambulation (measured in hours) from discharge from URPA","Up to 24 hours",null,{"allocation":48,"interventionModel":49,"interventionModelDescription":46,"primaryPurpose":50,"observationalModel":46,"timePerspective":46,"maskingInfo":51},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":52,"maskingDescription":46,"whoMasked":53},"DOUBLE",[54,55],"PARTICIPANT","INVESTIGATOR",[57,63],{"label":58,"type":59,"description":60,"interventionNames":61},"Echo-guided IPACK block","EXPERIMENTAL","IPACK block using 0.25% bupivacaine 15mL with adrenaline once.",[62],"Drug: IPACK block with Bupivacaine 0.25% with adrenaline",{"label":64,"type":65,"description":66,"interventionNames":67},"Echo-guided sciatic block","ACTIVE_COMPARATOR","Sciatic nerve block using 0.25% bupivacaine 15mL with adrenaline once.",[62],[69],{"type":70,"name":71,"description":72,"armGroupLabels":73,"otherNames":74},"DRUG","IPACK block with Bupivacaine 0.25% with adrenaline","The iPACK in performed in the popliteal fossa about 1 finger breath above the patella, ecoguided. That aims to anesthetize the articular branches to the posterior aspect of the knee in the popliteal region.",[58,64],[75],"Interspace between the Popliteal Artery and the Capsule of the posterior Knee",[77],{"name":78,"role":79,"phone":80,"phoneExt":46,"email":81},"Madalina Dinu, Mrs","CONTACT","0034600349517","madidinu@hotmail.com",[83],{"facility":84,"status":85,"city":86,"state":87,"zip":88,"country":89,"countryCode":90,"cosmosGeoPoint":91,"geoPoint":96,"contacts":97},"Hospital Universitari Germans Trias i Pujol","RECRUITING","Badalona","Barcelona","08916","Spain","ES",{"type":92,"coordinates":93},"Point",[94,95],2.24741,41.45004,{"lat":95,"lon":94},[98],{"name":99,"role":79,"phone":80,"phoneExt":46,"email":81},"Madalina Dinu",{"type":101,"investigatorFullName":102,"investigatorTitle":103,"investigatorAffiliation":5,"oldNameTitle":46,"oldOrganization":46},"PRINCIPAL_INVESTIGATOR","Dinu","Principal Investigator","100555613",false,"NCT06514365","Comparison of the Analgesic Effect of Subsartorial Saphenous Block and Popliteal Sciatic vs Subsartorial Saphenous Block and IPACK in Total Knee Replacement Surgery.","Comparison of the Analgesic Effect of Subsartorial Saphenous Block and Popliteal Sciatic vs Subsartorial Saphenous Block and IPACK in Total Knee Replacement Surgery. A Double Blind Randomized Clinical Trial.","Inclusion Criteria:\n\n* Patients with osteoarthritis scheduled for total primary knee arthroplasty with same surgeons\n* Locoregional anesthesia\n* Age equal to or greater than 18 years\n* Consent to participate in the study\n\nExclusion Criteria:\n\n* Age under 18 years old\n* General anesthesia\n* Allergy to local anesthetics\n* Severe kidney failure (Cr ≥ 2mg \u002F dL)\n* Chronic opioid use (over 3 months)\n* Chronic pregabalin \u002F gabapentin use (more than 3 months)\n* Psychiatric illness that may interfere with the evaluation or follow-up","FEMALE","18 Years",{"count":113,"type":114},62,"ESTIMATED","INTERVENTIONAL",[117],"NA","Total knee replacement surgery is associated with significant pain in the immediate postoperative period, especially in movement. In turn, this is associated with more subsequent chronic pain.\n\nThere are multiple options and the tendency is to perform increasingly distal nerve blocks to minimize limb weakness and thus allow early rehabilitation. In 2012, in an oral communication, Sanjay Sinha described a new nerve block called iPACK (\"Interspace between the Popliteal Artery and the Capsule of the posterior Knee\"). There are few studies on the efficacy of such a blockade so far, but none comparing the groups saphene + sciatic blocks vs. saphene + iPACK blocks.\n\nTherefore, this study aims to provide more information on the effectiveness this nerve blocks, in total knee replacement, in terms of analgesia and motor function.",[120,121,122],"Pain, Acute","Knee Osteoarthritis","Anesthesia",[124,125,126],"Ipack","Block","Total knee replacement","2024-07-16",{"date":129,"type":130},"2024-07-23","ACTUAL",{"date":132,"type":130},"2020-06-10",{"date":134,"type":114},"2024-08-01",{"name":5,"class":6},1]