About this trial

The aim of this study is to compare ultrasound-guided perineural injection of the median nerve with classic minimal incision surgical technique for median nerve decompression in patients diagnosed with mild, moderate, and severe carpal tunnel syndrome.

Eligibility criteria

Qualifiers

The presence of symptoms such as nocturnal, posture-related, or movement-related paresthesias, along with possible pain, in the area supplied by the median nerve in the hand, lasting for more than 3 months.

Confirmation of mild, moderate or severe CTS through electrophysiological testing.

Numbness and loss of sensation in the hand's regions innervated by the median nerve, as well as weakness in the thenar muscles innervated by the median nerve.

Positive results on either the Phalen test and/or Tinel sign.

Disqualifiers

Individuals who may exhibit symptoms mimicking carpal tunnel syndrome, such as cervical radiculopathy, polyneuropathy, brachial plexopathy, or thoracic outlet syndrome.

Patients who have received a previous injection into the carpal tunnel within the past 6 months.

Thenar muscle atrophy.

A history of prior carpal tunnel surgery.

Trial design

Treatments tested in this trial

  • Minimal Incision Surgery for median nerve decompression
  • Ultrasound-guided perineural injection with 5 cc 5% Dextrose

Treatment groups

60 Participants
are divided into 2 treatment groups

Locations

1
Afyonkarahisar Health Sciences University03200, Afyonkarahisar Turkey (Türkiye)

Sponsors and collaborators

Afyonkarahisar Health Sciences University

Lead sponsor