[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636110":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":35,"collaborators":10,"id":39,"slug":10,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":40,"sex":45,"minAge":46,"maxAge":10,"enrollmentInfo":47,"targetDuration":10,"studyType":50,"phases":10,"briefSummary":51,"conditions":52,"keywords":55,"overallStatus":21,"whyStopped":10,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},{"fullName":5,"class":6},"Arbor Research Collaborative for Health","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"External control: DOPPS cohort",null,"DOPPS study in Europe",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Roberto Pecoits-filho, MD","CONTACT","7342108046","Roberto.Pecoits@arborresearch.org",[19],{"facility":20,"status":21,"city":22,"state":10,"zip":10,"country":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"AURA","RECRUITING","Paris","France",{"type":25,"coordinates":26},"Point",[27,28],2.3488,48.85341,{"lat":28,"lon":27},[31,34],{"name":32,"role":15,"phone":16,"phoneExt":10,"email":33},"Pablo Urena, MD","urena.pablo@wanadoo.fr",{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Roberto Pecoits-Filho","Research Scientist","100636110",false,"NCT07561424","Comparisons Of Biochemical And Clinical Outcomes Of Hemodialysis Patients Treated With Middle Cut-Off Dialyzers Versus High-Flux Hemodialysis Or Hemodiafiltration","CONCORDIA","Inclusion Criteria\n\n* 18 years of age or older\n* Treated at an in-centre dialysis clinic\n* Receiving chronic, maintenance HD","ALL","18 Years",{"count":48,"type":49},1000,"ESTIMATED","OBSERVATIONAL","The CONCORDIA study is a retrospective, observational study evaluating clinical and biochemical outcomes among patients receiving maintenance hemodialysis with medium cut-off (MCO) dialyzers (Theranova) compared with high-flux hemodialysis (HF-HD) and hemodiafiltration (HDF). Using real-world data from non-DOPPS Theranova sites and the DOPPS cohort as an external control, the study aims to assess whether MCO dialyzers are associated with improved outcomes versus HF-HD and non-inferior outcomes compared with HDF. The primary outcome is all-cause mortality, with secondary outcomes including cardiovascular events, hospitalizations, infections, and laboratory measures related to anemia, mineral metabolism, and inflammation.",[53,54],"ESKD","Dialysis Patients",[56,57],"dialysis","HDF","2026-04-28",{"date":60,"type":61},"2026-05-01","ACTUAL",{"date":63,"type":61},"2026-02-01",{"date":65,"type":49},"2026-09-01",{"name":5,"class":6},1]