[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630846":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":28,"centralContacts":38,"locations":48,"responsibleParty":108,"collaborators":11,"id":111,"slug":11,"hasResults":112,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":112,"sex":118,"minAge":119,"maxAge":120,"enrollmentInfo":121,"targetDuration":11,"studyType":124,"phases":125,"briefSummary":127,"conditions":128,"keywords":132,"overallStatus":138,"whyStopped":11,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":148},{"fullName":5,"class":6},"Rigshospitalet, Denmark","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"LBB\u002FHIS-CRT group","EXPERIMENTAL",null,[13],"Procedure: HIS or LBBB -CRT",{"label":15,"type":10,"description":11,"interventionNames":16},"BiV-CRT group",[17],"Procedure: Conventional BiV-CRT",[19,24],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"PROCEDURE","HIS or LBBB -CRT","HIs pacing og LBB pacing at the implanteres discretion",[9],{"type":20,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"Conventional BiV-CRT","An LV-lead in a side-branch of the coronary sinus",[15],[29,33,35],{"name":30,"affiliation":31,"role":32},"Niels Risum Risum, MD, PhD","Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":31,"role":32},"michael vinther, MD, PhD",{"name":36,"affiliation":31,"role":37},"Berit Philbert","STUDY_CHAIR",[39,44],{"name":40,"role":41,"phone":42,"phoneExt":11,"email":43},"Niels Risum, MD, PhD","CONTACT","0045 35456995","niels.risum.01@regionh.dk",{"name":45,"role":41,"phone":46,"phoneExt":11,"email":47},"Michael Vinther, MD, PhD","0045 35456994","michael.vinther@regionh.dk",[49,65,79,94],{"facility":50,"status":11,"city":51,"state":11,"zip":52,"country":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Dept. of Cardiology, Aarhus University Hospital, Aarhus","Aarhus","8200","Denmark",{"type":55,"coordinates":56},"Point",[57,58],10.21076,56.15674,{"lat":58,"lon":57},[61],{"name":62,"role":41,"phone":63,"phoneExt":11,"email":64},"Jens Kristensen, MD, PhD","0045 29410644","jens.kristensen@auh.rm.dk",{"facility":66,"status":11,"city":67,"state":11,"zip":68,"country":69,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"Dept of Cardiology, Meilahti Hospital, Helsinki","Helsinki","00290","Finland",{"type":55,"coordinates":71},[72,73],24.93545,60.16952,{"lat":73,"lon":72},[76],{"name":77,"role":41,"phone":11,"phoneExt":11,"email":78},"Jarkko Karvonen Karvonen","jarkko.karvonen@hus.fi",{"facility":80,"status":11,"city":81,"state":11,"zip":82,"country":83,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Haukeland Universitetssykehus","Bergen","5009","Norway",{"type":55,"coordinates":85},[86,87],5.32415,60.39299,{"lat":87,"lon":86},[90],{"name":91,"role":41,"phone":92,"phoneExt":11,"email":93},"Torbjørn Lunde","0047 xxxxxxxx","torbjorn.lunde@gmail.com",{"facility":95,"status":11,"city":96,"state":11,"zip":11,"country":97,"cosmosGeoPoint":98,"geoPoint":102,"contacts":103},"Sahlgrenska University Hospital","Gothenburg","Sweden",{"type":55,"coordinates":99},[100,101],11.96679,57.70716,{"lat":101,"lon":100},[104],{"name":105,"role":41,"phone":106,"phoneExt":11,"email":107},"Amar Taha","0046 313427551","Amar.taha@vregionh.se",{"type":32,"investigatorFullName":109,"investigatorTitle":110,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Niels Risum","Md, PhD, Consultant cardiologist and electrophsiologist,","100630846",false,"NCT07492979","Conduction System Pacing vs. Biventricular Pacing for Cardiac Resynchronization Therapy","Nordic-CSP - a Randomized Nordic Study - Is Conduction System Pacing Superior Compared to Conventional BIV-CRT in Reducing the Death or Heart Failure-related Hospitalization in Patients With Heart Failure and Bundle Branch Block?","Nordic-CSP","Inclusion Criteria:\n\n* ≥18 years of age,\n* LVEF ≤ 35%,\n* NYHA Class II-IV (IV only outpatients),\n* optimized in medical treatment (OMT)\n\nAND one of the following:\n\n. LBBB according to AHA\u002FACC\u002FHRS Scientific Statement from 2009 and ≥130ms or\n\n* LBBB-like intraventricular conduction delay (IVCD) \\> 150ms or RV paced QRS and indication for upgrade to CRT (\\> 40% RV pacing) OR\n* ≥18 years of age,\n* LVEF ≤ 40 %\n* pacing indicated by AV-block and, thus, expected large percentage of ventricular pacing.\n\nExclusion Criteria:\n\n* recent acute myocardial infarction (AMI)\n* coronary artery bypass graft (CABG) (\\\u003C3 months)\n* life expectancy \\\u003C2 years, patients in hemodialysis\n* treatment with a cardiac implantable electronic device (CIED) is contraindicated.\n* Patients are excluded with regards to the MRI sub study if eGFR \\> 35 ml\u002Fmin, in case or contrast allergy or certain metal implants.","ALL","18 Years","99 Years",{"count":122,"type":123},1100,"ESTIMATED","INTERVENTIONAL",[126],"NA","The NORDIC-CSP trial is an investigator-initiated, blinded, nordic RCT aimed at evaluating whether using direct pacing of the HIS bundle (HIS)-pacing or left bundle branch (LBB) pacing is superior to conventional biventricular pacing in reducing the incidence of the composite endpoint of death and non-planned HF hospitalization. The study will be conducted in the 4 CRT-centres in Denmark and 6-8 centres from countries Sweden, Norway and Finland.",[129,130,131],"Cardiac Resynchronisation Therapy (CRT)","Heart Failure","Conduction System Pacing",[116,133,134,135,136,137],"conduction system pacing","His-pacing","LBB-pacing","Biventricular pacing","Cardiac Resynchronization Therapy","NOT_YET_RECRUITING","2026-03-20",{"date":141,"type":142},"2026-03-25","ACTUAL",{"date":144,"type":123},"2026-03-01",{"date":146,"type":123},"2031-07-01",{"name":5,"class":6},4]