About this trial

This pilot prospective study aims to evaluate adherence to home blood pressure monitoring using connected blood pressure (BP) devices in patients with malignant B-cell hemopathies initiating covalent Bruton tyrosine kinase inhibitors (cBTKi). The objective is to determine whether digital BP monitoring improves early detection and management of BTKi-induced hypertension over 6 months.

Eligibility criteria

Qualifiers

Age ≥18 years

Diagnosis of lymphoid malignancy: chronic lymphocytic leukemia, follicular lymphoma, marginal zone lymphoma, lymphoplasmacytic lymphoma, Waldenström macroglobulinemia, or mantle cell lymphoma

Initiation of oral BTK inhibitor therapy (ibrutinib, acalabrutinib, or zanubrutinib), in treatment-naive or relapsed patients

Affiliation with a social security system

Disqualifiers

Known cognitive impairment

No internet access

Individuals under guardianship, curatorship, or legal protection

Trial design

Treatments tested in this trial

  • Connected home blood pressure monitoring with daily IPA supervision.

Treatment groups

40 Participants
are divided into 1 treatment group

Locations

This trial has no locations

Sponsors and collaborators

Centre Hospitalier de la côte Basque

Lead sponsor