[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586206":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":36,"locations":44,"responsibleParty":143,"collaborators":146,"id":148,"slug":18,"hasResults":149,"nctId":150,"briefTitle":151,"officialTitle":152,"acronym":18,"eligibilityCriteria":153,"healthyVolunteers":149,"sex":154,"minAge":155,"maxAge":18,"enrollmentInfo":156,"targetDuration":18,"studyType":159,"phases":160,"briefSummary":162,"conditions":163,"keywords":165,"overallStatus":47,"whyStopped":18,"lastUpdateSubmitDate":168,"lastUpdatePostDateStruct":169,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":177},{"fullName":5,"class":6},"Université NAZI BONI","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CPAP group","EXPERIMENTAL","Continuous CPAP (with Boussignac valve) for the first 6-12 hours, then alternating with standard oxygen therapy. CPAP pressure= 7.5 cmH2O (25L\u002Fmin) then variations of +\u002F- 2.5 cmH20 according to clinical response and tolerance until weaning from oxygen or presence of intubation criteria",[13],"Other: CPAP",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard group","NO_INTERVENTION","Oxygen therapy as required using, simple face masks or high concentration face masks until there are criteria for intubation, or withdrawal from oxygen.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"CPAP","Continuous Positive Airway Pressure (CPAP) with Boussignac valve",[9],[25,29,33],{"name":26,"affiliation":27,"role":28},"Armand Mekontso-dessap, professor","Assistance Publique - Hôpitaux de Paris","STUDY_CHAIR",{"name":30,"affiliation":31,"role":32},"Ismael Guibla, doctor","University Hospital Souro Sanou, Burkina Faso","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":31,"role":35},"Ibrahim Alain Traore, professor","STUDY_DIRECTOR",[37,41],{"name":30,"role":38,"phone":39,"phoneExt":18,"email":40},"CONTACT","+22676135113","ismaelguibla@gmail.com",{"name":34,"role":38,"phone":42,"phoneExt":18,"email":43},"+22671457580","itraore80@gmail.com",[45,71,96,125],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Centre Hospitalier Universitaire Souro Sanou","RECRUITING","Bobo-Dioulasso","Houet","01 BP 676","Burkina Faso",{"type":53,"coordinates":54},"Point",[55,56],-4.29489,11.18064,{"lat":56,"lon":55},[59,63,64,67,69],{"name":60,"role":38,"phone":61,"phoneExt":18,"email":62},"Adama Decard Sawadogo, doctor","+22667337419","sadeca@gmail.com",{"name":30,"role":38,"phone":39,"phoneExt":18,"email":40},{"name":65,"role":66,"phone":18,"phoneExt":18,"email":18},"Jean Noel Savadogo, doctor","SUB_INVESTIGATOR",{"name":68,"role":32,"phone":18,"phoneExt":18,"email":18},"Sansan Armand Kambou, doctor",{"name":70,"role":66,"phone":18,"phoneExt":18,"email":18},"Ibrahim Alain Traore, Professor",{"facility":72,"status":73,"city":74,"state":75,"zip":76,"country":51,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"CHU Yalgado Ouedraogo","NOT_YET_RECRUITING","Ouagadougou","Kadiogo","03 BP 702250311655",{"type":53,"coordinates":78},[79,80],-1.53388,12.36566,{"lat":80,"lon":79},[83,87,91,93,95],{"name":84,"role":38,"phone":85,"phoneExt":18,"email":86},"Martin Lankoande, doctor","+22670606447","m.lansongui@gmail.com",{"name":88,"role":38,"phone":89,"phoneExt":18,"email":90},"Papougnezambo Bonkoungou, doctor","+22670415444","zambonkoungou@yahoo.fr",{"name":92,"role":66,"phone":18,"phoneExt":18,"email":18},"Souphiane Abou, doctor",{"name":94,"role":66,"phone":18,"phoneExt":18,"email":18},"Papougnezambo Bonkoungou, Professor",{"name":84,"role":32,"phone":18,"phoneExt":18,"email":18},{"facility":97,"status":73,"city":74,"state":75,"zip":98,"country":51,"cosmosGeoPoint":99,"geoPoint":101,"contacts":102},"CHU Tengandogo","03 BP 7067",{"type":53,"coordinates":100},[79,80],{"lat":80,"lon":79},[103,107,111,113,115,117,119,121,123],{"name":104,"role":38,"phone":105,"phoneExt":18,"email":106},"Imbe Ignace Yaro, doctor","+22670675148","yaroignace@gmail.com",{"name":108,"role":38,"phone":109,"phoneExt":18,"email":110},"Flavien Kabore, professor","+22670142327","kflavien72@yahoo.fr",{"name":112,"role":66,"phone":18,"phoneExt":18,"email":18},"Farid Pingwinde Belem, doctor",{"name":114,"role":66,"phone":18,"phoneExt":18,"email":18},"Fatou Fleur Sanou, doctor",{"name":116,"role":32,"phone":18,"phoneExt":18,"email":18},"Frida Djinkinde, doctor",{"name":118,"role":66,"phone":18,"phoneExt":18,"email":18},"Cheick Bougouma, doctor",{"name":120,"role":66,"phone":18,"phoneExt":18,"email":18},"Flavien Kabore, doctor",{"name":122,"role":66,"phone":18,"phoneExt":18,"email":18},"Ibrahim Kabre, doctor",{"name":124,"role":66,"phone":18,"phoneExt":18,"email":18},"Tewende Ouedraogo, doctor",{"facility":126,"status":73,"city":74,"state":75,"zip":127,"country":51,"cosmosGeoPoint":128,"geoPoint":130,"contacts":131},"CHU Bogodogo","14 BP 371",{"type":53,"coordinates":129},[79,80],{"lat":80,"lon":79},[132,136,140,141],{"name":133,"role":38,"phone":134,"phoneExt":18,"email":135},"Seif Idriss Salah Traore, doctor","+22670689698","seif_tis@yahoo.fr",{"name":137,"role":38,"phone":138,"phoneExt":18,"email":139},"Chamir Congo, doctor","+22673380662","congowendpanga20@gmail.com",{"name":137,"role":32,"phone":18,"phoneExt":18,"email":18},{"name":142,"role":66,"phone":18,"phoneExt":18,"email":18},"Jean Didier Sib, doctor",{"type":32,"investigatorFullName":144,"investigatorTitle":145,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Ismael Guibla","Clinical doctor",[147],{"name":27,"class":6},"100586206",false,"NCT06912360","Continous Positive Airway Pressure (CPAP) Support for Acute Hypoxemic Respiratory Failure in Burkina Faso","Use of (Continous Positive Airway Pressure) CPAP in the Management of Acute Hypoxemic Respiratory Failure","Inclusion Criteria:\n\nAll patients aged 18 years and older will be included in the study if they meet at least one of the following criteria :\n\n* Acute respiratory distress, defined as dyspnea respiratory rate ≥ 25 cycles\u002Fmin\n* Hypoxemia, defined as the need for more 6 liters of oxygen to maintain an oxygen saturation (SpO2) of ≥ 92%. The fraction of inspired oxygen (FiO2) will be estimated using the 3% rule.\n\nExclusion Criteria:\n\nPatients with any of the following criteria will not be included in the study:\n\n* Pregnant or breastfeeding women\n* Persons deprived of their liberty\n* Exacerbation of asthma, chronic obstructive pulmonary disease, or another chronic respiratory disease\n* Moderate to large amount of unilateral or bilateral undrained pleural effusion\n* Contraindication to CPAP: patient refusal, undrained pneumothorax, chest injury, repeated or large vomiting, upper gastrointestinal bleeding, craniofacial trauma, severe upper airway obstruction, or tetraplegia in the initial phase\n* Cardiac arrest, severe arrhythmias, shock requiring the use of vasopressors (norepinephrine, adrenaline, dopamine)\n* Altered level of consciousness (Glasgow Coma Scale score \\\u003C 13), repeated seizures, or status epilepticus\n* Medical decision to limit treatment: no intubation, no admission to intensive care\n* Refusal to participate in the study or participation in another interventional study on respiratory distress or acute respiratory failure.","ALL","18 Years",{"count":157,"type":158},240,"ESTIMATED","INTERVENTIONAL",[161],"NA","Acute respiratory failure (ARF) is a frequent medical emergency, involving high costs for health organizations and patients who often require intensive care and respiratory assistance. According to an international study, 61% of hypoxemic patients in intensive care receive invasive ventilation \\[3\\]. Invasive mechanical ventilation is often unavailable in low-income countries and non-invasive ventilatory supports such as continuous positive airway pressure (CPAP) and high-flow oxygen therapy (HFO) were very useful during the COVID-19 pandemic. They reduced the rate of intubation and ICU admissions. In addition, CPAP can be used without a ventilator, no electricity is required. So, it could be a support of choice in low-income countries.\n\nUsed of Boussignac-type CPAP could potentially reduce the recourse to intubation in patients with acute hypoxemic respiratory failure in a context where access to invasive ventilation remains very limited.",[164],"Acute Respiratory Failure",[21,166,167],"Acute hypoxemic respiratory failure","Africa","2025-07-23",{"date":170,"type":171},"2025-07-28","ACTUAL",{"date":173,"type":171},"2025-07-09",{"date":175,"type":158},"2026-02-20",{"name":5,"class":6},4]