Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age19+
SponsorChonnam National University Hospital
About this trial
To compare clinical outcomes of myocardial infarction with non-obstructive coronary arteries (MINOCA) according to the coronary microvascular dysfunction (CMD), evaluated by optical coherence tomography (OCT), invasive and non-invasive coronary physiologic assessment.
Eligibility criteria
Qualifiers
Subject with age ≥19 years and acute myocardial infarction
Rise and/or fall of cardiac troponin with one level >99 percentile plus ischemic signs/symptoms
Subject with non-obstructive coronary arteries
<50% diameter stenosis or
Disqualifiers
Subject with obstructive coronary arteries
Subject with alternate diagnosis including sepsis, pulmonary embolism, myocarditis, Takotsubo syndrome, spontaneous coronary dissection, and other cardiomyopathies.
Subject with cardiogenic shock or cardiac arrest ④ Subject who has non-cardiac co-morbid conditions with life expectancy <1 year ⑤ Subject or lactating women ⑥ Subject unable to provide consent
Trial design
Treatments tested in this trial
- Intravascular imaging (OCT), Invasive physiologic assessment (FFR, CFR, IMR), or Non-invasive physiologic assessment (N-13 ammonia PET)
Treatment groups
150 Participants
are divided into 2 treatment groupsLocations
1Chonnam National University Hospital61469, GwangjuGwangju, South Korea
Sponsors and collaborators
Chonnam National University Hospital
Lead sponsor
Korean Cardiac Research Foundation
Collaborator
Abbott
Collaborator
Source ClinicalTrials.gov